Handbook of venous thromboembolism / edited by Jecko Thachil and Catherine Bagot.

Format:

Book

Contributor:

Thachil, Jecko, editor.

Bagot, Catherine, editor.

Language:

English

Subjects (All):

Thrombophlebitis.

Physical Description:

1 online resource (331 pages) : illustrations, tables

Edition:

1st ed.

Place of Publication:

Chichester, England : Wiley-Blackwell, 2018.

Summary:

A clinically oriented handbook providing up-to-date recommendations for mastering the practical aspects of patient management for venous thromboembolism Venous thromboembolism (VTE) is associated with high morbidity and mortality both in and out of the hospital setting, and is one of the commonest reasons for hospital attendances and admissions. Designed as a practical resource, the Handbook of Venous Thromboembolism covers the practical aspects of venous thromboembolism management in short and easily followed algorithms and tables. This important text helps physicians keep up-to-date with the latest recommendations for treating venous thromboembolism in clinic-oriented settings. Experts in fields such as the radiological diagnosis of pulmonary embolism and thrombophilia testing, give a succinct summary of the investigation, diagnosis and treatment of venous thromboembolism and include evidence-based guidelines. With contributions from a team on internationally recognized experts, Handbook of Venous Thromboembolism is a source of information that specialists in the field can recommend to non-specialists and which the latter will be able to review to assist in their education and management of this wide-spread condition. This vital resource: * Comprises of a clinically focused handbook, useful as a daily resource for the busy physician * Offers a handbook written by an international team of specialists offering their experience on the practical aspects of venous thromboembolism management * Addresses venous thrombosis prevention, a major focus for healthcare providers * Includes coverage on controversies in the management of venous thromboembolism so clinicians can understand how experts are practicing in real scenarios Written for hematology trainees, emergency and acute medicine physicians, junior doctors, and primary care physicians, Handbook of Venous Thromboembolism covers the basics for treating patients with venous thromboembolism and offers guidelines from noted experts in the field.

Contents:

Intro

Title Page

Copyright Page

Contents

List of Contributors

Foreword

Section I Clinical Overview

Chapter 1 Risk Factors for Venous Thromboembolism

Introduction

Previous VTE

Surgery

Hospitalised Medical Patients

Cancer Associated Thrombosis (CAT)

Pregnancy

Combined Oral Contraceptive Use

Family History of VTE and Thrombophilia

Obesity

Travel

Substance Abuse

Conclusion

Further Reading

Chapter 2 Management of Venous Thrombosis in the Lower Limbs

Diagnosis

Treatment

Chapter 3 Clinical Presentation of Acute Pulmonary Embolism

Symptoms of Acute PE

Clinical Signs of Acute PE

Differential Diagnosis

Clinical Presentation in Specific Patient Subgroups

Clinical Presentation and Associated Prognosis

Summary

Section II Diagnosis

Chapter 4 Clinical Prediction Scores

Pulmonary Embolism

Deep Vein Thrombosis

Potential Pitfalls

Key Reading

Chapter 5 Laboratory Aspects in Diagnosis and Management of Venous Thromboembolism

Laboratory Diagnostics of Venous Thromboembolism

Laboratory Prediction of Recurrent Venous Thromboembolism

Laboratory Monitoring of Anticoagulant Therapy

References

Chapter 6 Thrombophilia Testing

Inherited Risk Factors

Acquired Risk Factors

Mixed Risk Factors

Indications for Thrombophilia Testing

Key Points

Chapter 7 Radiological Diagnosis of Pulmonary Embolism

Ventilation-perfusion Scanning (V/Q Scintigraphy)

Spiral Computed Tomography Pulmonary Angiography (CTPA)

The Issue of Subsegmental PE

Haemodynamic Assessment of Patients with PE

Latest Trends

Cost-effectiveness

Chapter 8 The Antiphospholipid Syndrome.

Antiphospholipid Antibodies: Epidemiology and Antigenic Specificities

Thrombosis

Management of APS

Management of Pregnancy

Management of Catastrophic APS

Review Articles

Guidelines

Section III Treatment

Chapter 9 Inpatient or Outpatient Anticoagulation

Sub-segmental Pulmonary Embolism

The Importance of a VTE Clinic

Chapter 10 An Anticoagulant Service in Practice

History

Current Organisation

Referral Process

Induction Appointments

Hospital Discharge Patients

Anticoagulant Clinic Structure

Self-testing Patients

Direct Oral Anticoagulants (DOACs)

The Future of GCAS

Chapter 11 Point of Care Testing

International Normalised Ratio (INR)

Quality Control

Comparison with Laboratory Results

Limitations of POC devices

POC D-dimer tests

Key Learning for POC INR Testing

Chapter 12 Direct Oral Anticoagulants in the Prevention and Management of Venous Thromboembolism

DOACs in treatment and prevention of Venous Thromboembolism: Introduction

Oral Direct Thrombin Inhibitors

Oral Xa Inhibitors

Systematic reviews and meta‐analyses of DOACs

Practical Issues for DOAC Usage

DOAC use in Specific Patient Subgroups

Chapter 13 The Role of Thrombolysis in the Management of Venous Thromboembolism

Rationale Behind CDT for Acute DVT

Pre-procedural Evaluation and Indications

Contraindications

Technical Aspects of CDT

CDT Pros and Cons

Outcomes for CDT in DVT

Thrombolysis in Pulmonary Embolism

Upper Extremity DVT

Chapter 14 Inferior Vena Cava Filters in the Management of Venous Thromboembolism

Introduction.

Evidence for IVCFs

Complications of IVCFs

IVCF Retrieval

IVCFs and Anticoagulation

Specific Indications for IVCF Placement

IVCF for Primary PE Prophylaxis

Disclosures

Section IV Special Situations

Chapter 15 VTE in Pregnancy

Incidence

Normal Physiological Changes of Pregnancy

Risk Factors

Thrombophilias

VTE Prophylaxis in Pregnancy

Diagnosis of VTE in pregnancy

Management

IVC Filters

VTE in Unusual Sites

Thrombophilia Screening

Massive PE/thrombolysis

Thrombolysis for PE in Pregnancy

Post-thrombotic Syndrome

Follow-up

Chapter 16 Paediatric Venous Thromboembolism

Paediatric Pathophysiology

Clinical Manifestations

Treatment Recommendations

Complications

Post-thrombotic Syndrome (PTS)

Chapter 17 Cancer-associated Thrombosis

Pathophysiology of Cancer‐associated Thrombosis

The Psychological Impact of CAT

Diagnosis of CAT

Challenges in the Management of CAT

Initial Treatment

Long-term Anticoagulation

Challenging Cases

Use of Inferior Vena Cava Filters

Thromboprophylaxis in Hospitalised Cancer Patients

Thromboprophylaxis in Ambulant Cancer Patients Receiving Chemotherapy

Chapter 18 Venous Thromboembolism Management in Obese Patients

Challenges of VTE Diagnosis

Treatment of VTE

Drugs Where Recognised Therapeutic Drug Monitoring Overcomes the Challenges of any Changes That Obesity May Have on Drug Pharmacokinetic Profiles

Chapter 19 Venous Thromboembolism in Intensive Care

Thromboprophylaxis or Not?.

Mechanical Thromboprophylaxis

Treatment of Venous Thromboembolism in the Critically Ill

Chapter 20 Venous Thromboembolism

a Primary Care Perspective

Prevention

Section V Unusual Site Thrombosis

Chapter 21 Cerebral Venous Thrombosis

Aetiology

Pathophysiology

Clinical Presentation

Secondary Prevention in Patients at Risk

Prognosis

Suggested Further Reading

Financial Disclosure

Chapter 22 Upper Extremity Thrombosis

Overview

Background and Classification

Epidemiology and Risk Factors

Approach to the Diagnosis of Suspected UEDVT

Interventional and Endovascular Therapies

Surgical Treatment

Management of CVC/PICC Devices with UEDVT

Prognosis and Complications

Chapter 23 Management of Intra-abdominal Thrombosis

Splanchnic Vein Thrombosis

Renal Vein Thrombosis

Ovarian Vein Thrombosis

Chapter 24 Thrombosis in the Retinal Circulation

Basic Eye Anatomy

Retinal Vein Occlusion

Retinal Artery Occlusion

Conclusions

Conflicts of Interest/disclosures

Section VI Long-term Sequelae of VTE

Chapter 25 Post-thrombotic Syndrome

Signs and Symptoms

Risk Factors for Developing PTS

Quality of Life

Scoring Systems

Investigations

Prevention Strategies

Chapter 26 Chronic Thromboembolic Pulmonary Hypertension

Epidemiology

Clinical Presentation and Patient Evaluation

Bibliography

Chapter 27 Predicting Recurrent VTE

Factors Influencing Risk of Recurrent VTE.

Clinical Prediction Rules for Recurrent VTE

Section VII Controversies

Chapter 28 Cancer Screening in Unprovoked Venous Thromboembolism

Chapter 29 Sub-segmental and Incidental PE - to Treat or Not?

Definitions

Who Gets Incidental/Subsegmental PE?

The Issue of Sub-segmental PE

Management Approach to Incidental/Sub-segmental PE

Chapter 30 Management of Distal Vein Thrombosis

Diagnosis of Distal Deep‐vein Thrombosis

Treatment of Isolated Distal Deep-vein Thrombosis

Section VIII Section VIII Prevention

Chapter 31 A Summary of the Evidence for VTE Prevention, with a Focus on the Controversies

Hospitalised Patients

Chapter 32 VTE Prevention: Real World Practice

The Strategy

Risk Assessment

Appropriate Thromboprophylaxis (TP)

Chapter 33 VTE Root Cause Analysis - How To Do It

Background

RCA Goes Political

the English Experience

Aims

Index

EULA.

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781119095583

1119095581

9781119095590

111909559X

9781119095606

1119095603

OCLC:

1012345215