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Biodefense research methodology and animal models / edited by James R. Swearengen.

Ebook Central Academic Complete Available online

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Format:
Book
Contributor:
Swearengen, James R.
Language:
English
Subjects (All):
Bioterrorism--Prevention--Research.
Bioterrorism.
Infection--Animal models.
Infection.
Communicable diseases--Research.
Communicable diseases.
Biological weapons.
Alternative toxicity testing.
Toxins--Research.
Toxins.
Physical Description:
1 online resource (415 p.)
Edition:
2nd ed.
Place of Publication:
Boca Raton, Fla. : CRC Press, 2012.
Boca Raton : CRC Press, 2012.
Language Note:
English
Summary:
Significant advances have been made in animal model development for biological research since the publication of the first edition of this volume, and the ramifications of the FDA's Animal Efficacy Rule have become better understood in the scientific community. With each chapter completely updated with the latest research findings, Biodefense Research Methodology and Animal Models, Second Edition spans the spectrum of coverage from basic research to advanced development of medical countermeasures.Topics discussed in this volume include:A history
Contents:
History of biological agents as weapons / James W. Martin
Bioterrorism and biowarfare : similarities and differences / Nelson W. Rebert
Scientific and ethical importance of animal models in biodefense research / James R. Swearengen and Arthur O. Anderson
Development and validation of animal models / Jaime B. Anderson and Kenneth Tucker
Infectious disease aerobiology : aerosol challenge methods / Chad J. Roy and Louise M. Pitt
Characterization of new and advancement of existing animal models of bacillus anthracis infection / Elizabeth K. Leffel and Louise M. Pitt
Glanders / David L. Fritz and David M. Waag
Plague / Jeffery J. Adamovicz and Patricia L. Worsham
Tularemia / Jeffery J. Adamovicz and David M. Waag
Q fever / David M. Waag and David L. Fritz
Brucellosis / Bret K. Purcell and Robert Rivard
Alphaviruses / William D. Pratt ... [et al.]
Orthopoxviruses / Peter B. Jahrling and Victoria Wahl-Jensen
Animal models for viral hemorrhagic fevers / Kelly l. Warfield and Thomas W. Geisbert
Botulinum toxins / Stephen B. Greenbaum, Jaime B. Anderson, and Frank J. Lebeda
Ricin / Stephen B. Greenbaum and Jaime B. Anderson
Staphylococcal and streptococcal superantigens : in vitro and in vivo assays / Teresa Krakauer and Bradley G. Stiles.
Notes:
Description based upon print version of record.
Includes bibliographical references.
Description based on metadata supplied by the publisher and other sources.
ISBN:
9786613525796
9781040210291
1040210295
9780429152276
0429152272
9781280121937
1280121939
9781439836330
1439836337
OCLC:
778448453

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