Molecular machines : a materials science approach / Giovanni Zocchi.

Format:

Book

Author/Creator:

Zocchi, Giovanni, author.

Series:

Princeton scholarship online.

Princeton scholarship online

Language:

English

Subjects (All):

Molecular biology.

Biomolecules.

Microbiology.

Physical Description:

1 online resource (189 pages) : illustrations

Place of Publication:

Princeton, NJ : Princeton University Press, [2018]

Language Note:

In English.

Summary:

Molecular Machines presents a dynamic new approach to the physics of enzymes and DNA from the perspective of materials science. Unified around the concept of molecular deformability-how proteins and DNA stretch, fold, and change shape-this book describes the complex molecules of life from the innovative perspective of materials properties and dynamics, in contrast to structural or purely chemical approaches. It covers a wealth of topics, including nonlinear deformability of enzymes and DNA; the chemo-dynamic cycle of enzymes; supra-molecular constructions with internal stress; nano-rheology and viscoelasticity; and chemical kinetics, Brownian motion, and barrier crossing. Essential reading for researchers in materials science, engineering, and nanotechnology, the book also describes the landmark experiments that have established the materials properties and energy landscape of large biological molecules.Molecular Machines is also ideal for the classroom. It gives graduate students a working knowledge of model building in statistical mechanics, making it an essential resource for tomorrow's experimentalists in this cutting-edge field. In addition, mathematical methods are introduced in the bio-molecular context-for example, DNA conformational transitions are used to illustrate the transfer matrix formalism. The result is a generalized approach to mathematical problem solving that enables students to apply their findings more broadly.Molecular Machines represents the next leap forward in nanoscience, as researchers strive to harness proteins, enzymes, and DNA as veritable machines in medicine, technology, and beyond.

Contents:

Frontmatter

Contents

Preface

1. Brownian Motion

2. Statics of DNA Deformations

3. Kinematics of Enzyme Action

4. Dynamics of Enzyme Action

Bibliography

Index

Notes:

Includes bibliographical references and index.

Previously issued in print: 2018.

Description based on online resource; title from PDF title page (publisher's Web site, viewed 23. Mai 2019)

ISBN:

9781523124602

1523124601

9781400890064

1400890063

OCLC:

1036781636