Lipoxygenases in Inflammation / edited by Dieter Steinhilber.

Format:

Book

Contributor:

Steinhilber, Dieter, 1959- editor.

SpringerLink (Online service)

Series:

Medicine (Springer-11650)

PIR (Series) 0379-0363

Progress in Inflammation Research, 0379-0363

Language:

English

Subjects (All):

Immunology.

Lipids.

Enzymes.

Human physiology.

Lipidology.

Enzymology.

Human Physiology.

Local Subjects:

Immunology.

Lipidology.

Enzymology.

Human Physiology.

Physical Description:

1 online resource (XI, 245 pages) : 39 illustrations, 26 illustrations in color.

Edition:

First edition 2016.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2016.

System Details:

text file PDF

Summary:

Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.

Contents:

Introduction into lipoxygenases

5-Lipoxygenase

Leukotriene A4 hydrolase and LTC4 synthase

Catalytic multiplicity of 15-lipoxygenase-1 orthologs (ALOX15) of different species

Platelets and lipoxygenases

Lipoxygenases and cardiovascular diseases

Role of lipoxygenases in pathogenesis of cancer

The physiology and pathophysiology of lipoxygenases in the skin

5-Oxo-ETE and inflammation

Lipoxins, resolvins, and the resolution of inflammation.

Other Format:

Printed edition:

ISBN:

978-3-319-27766-0

9783319277660

Access Restriction:

Restricted for use by site license.