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Trauma Induced Coagulopathy / edited by Eduardo Gonzalez, Hunter B. Moore, Ernest E. Moore.

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Springer Nature - Springer Medicine eBooks 2016 English International Available online

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Format:
Book
Contributor:
Gonzalez, Eduardo, MD, editor.
Moore, Hunter B., editor.
Moore, Ernest Eugene, editor.
SpringerLink (Online service)
Series:
Medicine (Springer-11650)
Language:
English
Subjects (All):
Trauma.
Critical care medicine.
Surgery.
Anesthesiology.
Traumatic Surgery.
Intensive / Critical Care Medicine.
General Surgery.
Local Subjects:
Traumatic Surgery.
Intensive / Critical Care Medicine.
General Surgery.
Anesthesiology.
Physical Description:
1 online resource (XXXI, 601 pages) : 119 illustrations, 75 illustrations in color
Edition:
First edition 2016.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2016.
System Details:
text file PDF
Summary:
This text is aimed at defining the current concepts that define trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It will serve as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader will have full understanding of the tests that are used to study trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications are reviewed in detail. Trauma Induced Coagulopathy will also be a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy.
Contents:
Cell-Mediated Hemostasis
Antithrombin Contributions to Physiological Hemostasis and Thrombosis Prevention, and its Dysregulation in Trauma and TIC
Physiology of Hemostasis: Plasmin-antiplasmin system
Thrombin Formation
Fibrinogen
Activated Protein C
Pathogenesis of Trauma Induced Coagulopathy: The Endothelium
Platelets
Fibrinolysis
Neutrophils, Inflammation and Innate Immunity in Trauma-Induced Coagulopathy
DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis
The Complement System and Coagulation
Disseminated Intravascular Coagulation
Prothrombin and Partial Thromboplastin Time
Fibrinogen Assays
Platelet Aggregometry
Thrombelastography
Rotational Thromboelastometry (ROTEM®)
Red Blood Cell: Manufacture, Storage, and Transfusion
Plasma Transfusion
Cryoprecipitate Transfusion
The Evolving Role of Platelets in Trauma Care
Massive Transfusion Protocols
Fibrinogen and Clotting Factor Replacement
Anti-Fibrinolytics
Venous Thromboembolism
Congenital and Acquired Hypercoagulable States
Coagulopathy in Traumatic Brain Injury (TBI)
Liver Disease
Hemostatic Abnormalities in Renal Disease
Pediatrics
Pregnancy
Management of Chronically Anticoagulated Patients
Animal Models
.
Other Format:
Printed edition:
ISBN:
978-3-319-28308-1
9783319283081
Access Restriction:
Restricted for use by site license.

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