Drosophila glia / LinFang Wang, Honglei Wang, and Margaret S. Ho.

Format:

Book

Author/Creator:

Wang, Linfang (Scientist), author.

Wang, Honglei (Scientist), author.

Ho, Margaret S., author.

Series:

Colloquium digital library of life sciences

Colloquium series on neuroglia in biology and medicine ; #12.

Colloquium series on neuroglia in biology and medicine: from physiology to disease ; #12

Language:

English

Subjects (All):

Neuroglia.

Drosophila melanogaster.

Physical Description:

1 online resource (x, 43 pages) : illustrations (some color).

Place of Publication:

[San Rafael, California] : Morgan & Claypool Life Sciences, [2019]

System Details:

Mode of access: World Wide Web.

System requirements: Adobe Acrobat reader.

text file

Summary:

Glia, the non-neuronal cells in the nervous systems, are both passive and active participants in diverse arrays of neuronal function. The diversity of glial cells in various animal species appears to be correlated with the complexity of brains. In the animal Drosophila melanogaster, glia are similarly categorized to their mammalian counterparts in morphology and function. Surface glia cover the outermost surface of the brain and function as a blood-brain-barrier to protect the nervous system. Cortex glia, similar to mammalian astrocytes, enwrap around the neuronal cell bodies and provide trophic support. Neuropil glia, similar to mammalian astrocytes and oligodendrocytes, are closely associated with the synapse-enriched neuropils and regulate synapse formation, synaptic function, and underlie the mechanism of circuit and behavior. This short monograph focuses on Drosophila glia, discusses the classification of different glial subtypes and their developmental origins, and provides an overview of different glial-mediated activity crucial for the development and function of the nervous system. This context serves as a general introduction to the molecular and cellular basis of glial function in normal and pathological brains.

Contents:

1. Drosophila glia

2. Classification and developmental origins

2.1. Neuropil glia

2.2. Surface glia

2.3. Cortex glia

3. Drosophila glial function

3.1. Glia as stem cell niche

3.2. Glial function in the "blood-brain barrier (BBB)"

3.3. Glial function at synapses

3.4. Glial function in axon pruning and neuronal remodeling

3.5. Glia in normal behavior

4. Glia in drosophila models of neurological disorders.

Notes:

Part of: Colloquium digital library of life sciences.

Includes bibliographical references (pages 29-42).

Title from PDF title page (viewed on April 2, 2019).

Other Format:

Print version:

ISBN:

9781615047987

OCLC:

1091193637

Access Restriction:

Restricted for use by site license.