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Basic and applied bone biology edited by David B. Burr, Matthew R. Allen
- Format:
- Book
- Language:
- English
- Subjects (All):
- Bones.
- Bone and Bones.
- bone (material).
- Medical Subjects:
- Bone and Bones.
- Physical Description:
- 1 online resource (xvii, 460 pages) illustrations (some color)
- Edition:
- Second edition
- Place of Publication:
- London, United Kingdom Academic Press, an imprint of Elsevier [2019]
- System Details:
- text file
- Contents:
- Front Cover
- BASIC AND APPLIED BONE BIOLOGY
- Copyright
- Dedication
- Contents
- List of Contributors
- Biographies
- Preface (First Edition)
- Preface (Second Edition)
- I
- BASIC BONE BIOLOGY AND PHYSIOLOGY
- 1
- Bone Morphology and Organization
- THE FUNCTIONS OF BONE
- BONE IS ORGANIZED AS A MULTISCALE MATERIAL
- BONE COMPOSITION
- THE NANOSCALE ORGANIZATION OF BONE
- Collagen
- Enzymatically Mediated Collagen Cross-Linking
- Nonenzymatically Mediated Collagen Cross-Linking
- Collagen Orientation
- Bone Mineral
- Noncollagenous Extracellular Matrix Proteins
- Proteoglycans and Glycosaminoglycans
- Glycoproteins
- SIBLING Proteins
- Osteocalcin
- Osteonectin
- THE MICROSTRUCTURAL ORGANIZATION OF BONE
- Woven Bone
- Primary Bone
- Primary Lamellar Bone
- Plexiform Bone
- Primary Osteons
- Secondary Bone
- Interstitial Bone
- THE MACROSCOPIC ORGANIZATION OF BONE
- Cortical Bone
- Skeletal Envelopes
- THE BLOOD SUPPLY AND INNERVATION OF BONE
- Blood Supply
- Innervation of Bone
- BONE FLUID COMPARTMENTS
- BONE MASS AND BONE QUALITY
- Rate of Bone Turnover
- Bone Trabecular Architecture
- Tissue Material (Intrinsic) Properties
- Microdamage Accumulation
- Suggested Readings
- 2
- Bone Marrow and the Stem Cell Niche
- NICHES IN DEVELOPMENT
- IMAGING OF NICHES
- BONE MARROW NICHE CELLS
- Nonhematopoietic
- Osteoblastic Cells
- Mesenchymal Stromal/Stem Cell Populations
- Adipocytes
- Endothelial Cells
- Hematopoietic
- Megakaryocytes
- Macrophages
- Neutrophils
- Osteoclasts
- NEURONAL REGULATION OF THE HEMATOPOIETIC STEM CELL NICHE
- HORMONAL REGULATION OF THE HEMATOPOIETIC STEM CELL NICHE
- NICHES AND MALIGNANCIES
- AGING AND THE BONE MARROW MICROENVIRONMENT
- THE FUTURE
- 3
- Bone Cells
- OSTEOCLASTS
- Osteoclast Morphology and Function
- Osteoclast Differentiation and Fusion
- Osteoclast Apoptosis
- Regulation of Osteoclast Generation and Survival
- OSTEOBLASTS
- Osteoblast Morphology and Function
- Osteoblast Formation and Differentiation
- Osteoblast Apoptosis
- Regulation of Osteoblast Generation and Survival
- Bone Lining Cells
- OSTEOCYTES
- Osteocyte Morphology and Functions
- Osteocytogenesis and Osteocyte Maturation
- Osteocyte Apoptosis: Consequences and Regulation
- Preservation of Osteocyte Viability by Mechanical Stimuli
- Aging and Osteocyte Apoptosis
- Hormonal Regulation of Osteocyte Life Span
- Regulation of Bone Formation by Osteocytes: The Sclerostin Paradigm
- Regulation of Bone Resorption by Osteocytes: RANKL and OPG
- Regulation of Bone Mineralization by Osteocytes
- 4
- Local Regulation of Bone Cell Function
- OVERVIEW OF CYTOKINES AND GROWTH FACTORS AND THEIR RECEPTORS
- Definition: Cytokines Versus Growth Factors
- Soluble Ligands
- Membrane-Bound Ligands
- Receptor Classification
- Signal Transduction Cascades
- Notes:
- Includes index.
- Includes bibliographical references and index
- Online resource; title from PDF title page (ScienceDirect, viewed February 27, 2019)
- Other Format:
- Print version Basic and applied bone biology.
- ISBN:
- 9780128132609
- 0128132604
- OCLC:
- 1088558283
- Access Restriction:
- Restricted for use by site license
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