Accurate results in the clinical laboratory a guide to error detection and correction edited by Amitava Dasgupta, Jorge L. Sepulveda

Format:

Book

Contributor:

Dasgupta, Amitava, 1958- editor.

Sepulveda, Jorge L., editor.

Language:

English

Subjects (All):

Diagnosis, Laboratory--Quality control.

Diagnosis, Laboratory.

Medical laboratories--Quality control.

Medical laboratories.

Quality control.

Clinical Laboratory Techniques--standards.

Clinical Laboratory Techniques--methods.

Diagnostic Errors--prevention & control.

Quality Control.

Diagnostic Tests, Routine--standards.

Medical Laboratory Science--standards.

Laboratories.

quality control.

Evidence-based medicine.

Medical Subjects:

Clinical Laboratory Techniques--standards.

Clinical Laboratory Techniques--methods.

Diagnostic Errors--prevention & control.

Quality Control.

Diagnostic Tests, Routine--standards.

Medical Laboratory Science--standards.

Laboratories.

Genre:

Electronic books

Physical Description:

1 online resource (xvii, 491 pages) illustrations (some color)

Edition:

Second edition

Place of Publication:

Amsterdam Elsevier [2019]

System Details:

text file

Summary:

"Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, Second Edition, provides a comprehensive review of the factors leading to errors in all areas of clinical laboratory testing. This trusted guide addresses interference issues in all laboratory tests, including patient epigenetics, processes of specimen collection, enzymes and biomarkers"--Publisher's description

Contents:

I: Sources of errors in clinical laboratories: an overview. Variation, errors, and quality in the clinical laboratory

Errors in patient preparation, specimen collection, anticoagulant and preservative use: how to avoid such pre-analytical errors

Sample processing and specimen misidentification issues: major sources of pre-analytical errors

Effect of patient-related factors on clinical laboratory test results

Interferences of hemolysis, lipemia and high bilirubin on laboratory tests

Immunoassay design

Overview of other sources of interferences in immunoassays: prozone effect and interferences from heterophilic antibodies and autoantibodies

Biotin interference in clinical laboratory tests: sporadic problem or a serious clinical issue?

II: Sources of errors in clinical chemistry laboratory. Challenges in routine clinical chemistry testing analysis of small molecules

Challenges in routine clinical chemistry analysis: proteins and enzymes

Challenges in endocrinology testing

Pitfalls in testing for common tumor markers

III: Sources of errors in therapeutic drug monitoring and toxicology. Issues of interferences in therapeutic drug monitoring

Limitations of immunoassays for screening of drugs of abuse in urine: issues of false positive and false negative results

Challenges in confirmation testing for drugs of abuse

Issues of false negative results in toxicology: difficult in detecting certain drugs and issues with detection of synthetic cathinone (bath salts), synthetic cannabinoids (spice), and other new psychoactive substances

Ethanol determination using automated analyzers: limitations and pitfalls

IV: Herbal medicines and laboratory testings. Effects of herbal supplements on clinical laboratory test results

V: Sources of errors in immunology laboratory. Critical issues in hemoglobinopathy detection and serology testing for HIV and hepatitis infections

Sources of errors in immunology and serology testing

VI: Sources of errors in molecular, genetic and related testings. Sources of error in molecular diagnostic analyses

Molecular testing for targeted therapies and pharmacogenomics

Challenges and sources of inaccuracy in biochemical genetics testing

VII: Sources of errors in microbiology testings. Sources of pre-analytical, analytical and post-analytical errors in the microbiology laboratory

VIII: Sources of errors in hematology and coagulation testings. Sources of errors in hematology testing

Sources of errors in coagulation testing

Sources of errors in flow cytometry

IX: Sources of errors in transfusion medicine. Interferences in blood bank testing

Errors and adverse effects of blood transfusion

X: Sources of errors in point of care testing. Methodological issues in point of care testing devices

Special concern: sources of inaccuracy in breath alcohol analysis

Notes:

Revised edition of: Accurate results in the clinical laboratory : a guide to error detection and correction / edited by Amitava Dasgupta, Jorge L. Sepulveda. 2013

Includes bibliographical references and index

Online resource; title from resource home page (ScienceDirect, viewed September 4, 2020)

Print version record

Other Format:

Print version Accurate results in the clinical laboratory.

ebook version

ISBN:

9780128137772

0128137770

OCLC:

1110484425

Access Restriction:

Restricted for use by site license