Mass spectrometry for drug discovery and drug development / edited by Walter A. Korfmacher.

Format:

Book

Contributor:

Korfmacher, Walter A.

ProQuest (Firm)

Series:

Wiley-Interscience series on mass spectrometry

Wiley series on mass spectrometry

Language:

English

Subjects (All):

Drugs--Analysis.

Drugs.

Mass spectrometry.

Genre:

Electronic books.

Physical Description:

1 online resource (xii, 461 pages) : illustrations.

Place of Publication:

Hoboken, N.J. : John Wiley and Sons, [2013]

System Details:

text file

Contents:

1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gerard Hopfgartner

2. Utility of high resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang

3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia

4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou

5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash

6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky

7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak

8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion

9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendraÿ N. Pramanik

10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli

11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer

12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury

13. Mass spectrometry of siRNA / Mark Cancilla and Mike Flanagan

14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily

15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high resolution full scan? / Lieve Dillen and Filip Cuyckens.

Notes:

Includes bibliographical references and index.

Electronic reproduction. Ann Arbor, MI : ProQuest, 2015. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries.

OCLC:

823389939

Access Restriction:

Restricted for use by site license.