Single-chain polymer nanoparticles : synthesis, characterization, simulations, and applications / edited by Jose A. Pomposo.

Format:

Book

Contributor:

Pomposo, José A., editor.

Series:

THEi Wiley ebooks.

THEi Wiley ebooks

Language:

English

Subjects (All):

Polymers.

Nanoparticles.

Physical Description:

1 online resource (419 pages)

Edition:

1st ed.

Place of Publication:

Wienheim, Germany : Wiley-VCH, 2017.

System Details:

Access using campus network via VPN at home (THEi Users Only).

Summary:

This first book on this important and emerging topic presents an overview of the very latest results obtained in single-chain polymer nanoparticles obtained by folding synthetic single polymer chains, painting a complete picture from synthesis via characterization to everyday applications. The initial chapters describe the synthetics methods as well as the molecular simulation of these nanoparticles, while subsequent chapters discuss the analytical techniques that are applied to characterize them, including size and structural characterization as well as scattering techniques. The final chapters are then devoted to the practical applications in nanomedicine, sensing, catalysis and several other uses, concluding with a look at the future for such nanoparticles. Essential reading for polymer and materials scientists, materials engineers, biochemists as well as environmental chemists.

Contents:

Cover

Title Page

Copyright

Contents

List of Contributors

Preface

Chapter 1 Synthetic Methods Toward Single-Chain Polymer Nanoparticles

1.1 Introduction

1.2 Single-Chain Rings via Irreversible and Reversible Bonds

1.3 Single-Chain Nanoparticles via Irreversible Bonds

1.4 Single-Chain Nanoparticles via Supramolecular Chemistry

1.5 Single-Chain Nanoparticles Based on Dynamic Covalent Chemistry

1.6 Conclusions and Outlook

Acknowledgments

References

Chapter 2 Computer Simulations of Single-Chain Nanoparticles

2.1 Computer Simulations in Soft Matter Science

2.2 Simulation of Single-Chain Nanoparticles: Antecedents

2.3 A Bead-Spring Model for Single-Chain Nanoparticles

2.4 Conventional Routes in Good Solvent: Sparse Single-Chain Nanoparticles

2.4.1 The Simple Case: SCNPs from Homofunctional Precursors

2.4.2 SCNPs Synthesis via Orthogonal and Multi-orthogonal Protocols

2.5 Routes to Globular Single-Chain Nanoparticles

2.5.1 Bonding Mediated by Long Linkers

2.5.2 Solvent-Assisted Routes

2.6 Sparse SCNPs: Analogies with Intrinsically Disordered Proteins

2.7 Globular SCNPs: A New Class of Soft Colloids

2.8 Conclusions and Outlook

2.8.1 SCNPs as Nanofillers in All-Polymer Nanocomposites

2.8.2 Nonlinear Rheology of SCNPs

2.8.3 SCNPs under Pulling Forces

Chapter 3 Characterization of Single-Chain Polymer Nanoparticles: Analytical Techniques

3.1 Introduction

3.2 Single-Chain Polymer Nanoparticle Characterization via Size Exclusion Chromatography (SEC)

3.2.1 Standard Calibration SEC

3.2.2 Measuring Single-Chain Polymer Nanoparticle Formation via SEC-MALS

3.2.3 Measuring Single-Chain Polymer Nanoparticle Formation via SEC and Viscometry

3.3 Spectroscopic Characterization of Single-Chain Polymer Nanoparticles.

3.3.1 Single-Chain Polymer Nanoparticle Characterization via Standard 1D 1H NMR

3.3.2 Single-Chain Polymer Nanoparticle Characterization via Other Nuclei 1D NMR

3.3.3 Single-Chain Polymer Nanoparticle Structural and Conformational Characterization via NMR

3.3.4 Single-Chain Polymer Nanoparticle Characterization via IR, UV-vis, CD, and Fluorescence Spectroscopy

3.4 Characterization of Single-Chain Polymer Nanoparticle Morphology

3.4.1 Morphological Characterization via TEM

3.4.2 Morphological Characterization via AFM

3.4.3 Morphological Characterization via Scattering

3.5 Conclusions and Outlook

Chapter 4 Structure and Dynamics of Systems Based on Single-Chain Polymer Nano-Particles Investigated by Scattering Techniques

4.1 Introduction

4.2 Scattering Experiments

4.3 Sources and Instrumentation

4.3.1 Sources

4.3.2 Diffraction

4.3.3 Quasielastic Neutron Scattering

4.4 Application of Scattering Techniques to Polymeric Systems

4.4.1 Polymer Melts

4.4.2 Polymer Solutions

4.5 SCNPs in Dilute Solution

4.5.1 How Globular Are SCNPs in Good Solvent?

4.5.2 Chain Dynamics

4.6 SCNPs in Bulk

4.7 All-Polymer Nano-Composites: SCNPs Dispersed in a Linear Polymer Matrix

4.7.1 Interpenetration of the Components

4.7.2 Dynamic Asymmetry

4.7.3 Selecting Component Contributions by Deuterium Labeling

4.7.4 Dynamics of SCNPs Observed by QENS

4.7.5 Linear Polymer Matrix Dynamics

4.8 SCNPs as Confining Medium of Linear Chains

4.9 Conclusions

Chapter 5 Dynamically Folded Single-Chain Polymeric Nanoparticles

5.1 Introduction

5.2 Single-Chain Polymeric Nanoparticles versus Conventional Nanoparticles

5.3 Preparation of Dynamically Folded Single-Chain Polymeric Nanoparticles.

5.4 Characterization of Dynamically Folded Single-Chain Polymer Nanoparticles

5.5 Conclusions and Future Outlook

Chapter 6 Metal Containing Single-Chain Nanoparticles

6.1 Introduction

6.2 Palladium

6.3 Iron

6.4 Copper

6.5 Other Metals

6.5.1 Rhodium, Iridium, and Nickel

6.5.2 Ruthenium

6.5.3 Zinc

6.5.4 Gold

6.5.5 Gadolinium

6.5.6 Gallium

6.6 Conclusions and Outlook

Chapter 7 Colloidal Unimolecular Polymer Particles: CUP

7.1 Introduction

7.2 Synthesis

7.2.1 Monomers and Ratio, Molecular Weight, Glass Transition, Cup Size, and Functionality

7.2.2 Reduction and CUP Formation

7.2.3 Collapse Point

7.2.4 CUP Size and Distribution Correlation to Molecular Weight

7.3 Theory of the Formation of CUP Particles

7.3.1 Entropy Effect/Soap Theory

7.3.2 Hydrophilic/Lipophilic Balance (HLB)

7.3.3 Flory-Huggins Theory

7.4 Conformation of the CUP Particles

7.5 Electrokinetic Behavior in CUPs

7.5.1 Zeta Potential, Debye-Hückel Parameter and Electrophoretic Mobility

7.5.2 Determining the Effective Nuclear Charge

7.5.2.1 Nernst-Einstein Model

7.5.2.2 Hessingers Model

7.5.2.3 Charge Renormalization

7.5.3 Electrokinetic Behavior in COO- CUPs

7.6 Electroviscous Effect in CUPs

7.6.1 Electroviscous Effect: Theory

7.6.1.1 Primary Electroviscous Effect

7.6.1.2 Secondary Electroviscous Effect

7.6.1.3 Tertiary Electroviscous Effect

7.6.2 Intrinsic Viscosity Determination

7.6.3 Surface Water Determination

7.6.4 Electroviscous Effect in CUPs

7.6.4.1 Electroviscous Effect in COO- CUPs

7.6.4.2 Electroviscous Effect in SO3- CUPs

7.6.4.3 Electroviscous Effect in QUAT CUPs

7.6.5 Effect of Salts on Rheology

7.7 Gel Point Behavior

7.7.1 Packing in CUPs

7.7.2 Gel Point Study

7.7.2.1 Determination of Gel Point.

7.7.2.2 Viscosity Measurements

7.7.2.3 Maximum Packing Volume Fraction, Density, and Thickness of Surface Water

7.7.3 Comparison with Commercial Resins like Latex and Polyurethane Dispersions

7.8 Surface Tension Behavior

7.8.1 Equilibrium Surface Tension Behavior

7.8.1.1 Effect of Concentration on Equilibrium Surface Tension

7.8.1.2 Effect of Molecular Weight on Equilibrium Surface Tension

7.8.1.3 Effect of Surface Active Groups on Equilibrium Surface Tension

7.8.2 Dynamic Surface Tension Behavior

7.8.2.1 Effect of Molecular Weight on Kinetic Relaxation Time

7.8.2.2 Effect of Concentration on Kinetic Relaxation Time

7.8.2.3 Effect of Molecular Weight on Dynamic Surface Tension

7.8.2.4 Effect of Concentration on Dynamic Surface Tension

7.9 Cup Surface Water

7.9.1 Electroviscous Effect and Gel Point

7.9.2 Differential Scanning Calorimetry

7.9.3 NMR Relaxation Study

7.9.3.1 Proton NMR Spin-Lattice Relaxation Time Constant versus CUP Concentration

7.9.3.2 Proton NMR Spin-Lattice Relaxation Time Constant versus Temperature

7.9.3.3 Calculation of Bound Water Amount

7.10 Study of Core Environment of CUPs

7.10.1 F19 NMR T2 Relaxation Experiment

7.11 Applications: Use of CUPs in Coatings

7.11.1 Acrylic CUP Coating Lacquers

7.11.2 Aziridine-Cured Acrylic CUPs Resin

7.11.3 Use of CUPs with Melamine Resin Cross-Linking

7.11.4 Use of Sulfonate CUPs as Catalyst for Melamine Cure Systems

7.11.5 Epoxy

7.11.6 Use of CUPs as Additive for Freeze-Thaw Stability and Wet Edge Retention

Chapter 8 Single-Chain Nanoparticles via Self-Folding Amphiphilic Copolymers in Water

8.1 Introduction

8.2 Single-Chain Folding Amphiphilic Random Copolymers

8.2.1 Hydrophobic Alkyl Pendants

8.2.2 Hydrophobic/Hydrogen-Bonding Pendants

8.2.3 Fluorous Perfluorinated Pendants.

8.3 Precision Self-Assembly and Self-Sorting of Amphiphilic Random Copolymers

8.4 Single-Chain Crosslinked Star Polymers

8.5 Conclusions and Future Directions

Chapter 9 Applications of Single-Chain Polymer Nanoparticles

9.1 Introduction

9.1.1 Single-Chain Soft Nano-Objects

9.1.2 Reversible versus Irreversible Single-Chain Polymer Nanoparticles

9.1.3 Main Applications of Single-Chain Polymer Nanoparticles

9.2 Nanomedicine

9.2.1 Controlled Drug Delivery Systems

9.2.1.1 Single-Chain Polymer Nanoparticles for Controlled Delivery of Chiral Amino Acid Derivatives

9.2.1.2 Single-Chain Polymer Nanoparticles for Controlled Delivery of Peptides

9.2.1.3 Single-Chain Polymer Nanoparticles for Controlled Delivery of Vitamins

9.2.1.4 Single-Chain Polymer Nanoparticles for Controlled Delivery of Drugs

9.2.2 Image Contrast Agents

9.2.2.1 Single-Chain Polymer Nanoparticles for Magnetic Resonance Imaging

9.2.2.2 Single-Chain Polymer Nanoparticles for Single Photon Emission Computerized Tomography

9.2.2.3 Single-Chain Polymer Nanoparticles for Fluorescence Imaging

9.3 Catalysis

9.3.1 Single-Chain Polymer Nanoparticles as Nanoreactors for the Synthesis of Chemical Compounds

9.3.2 Single-Chain Polymer Nanoparticles as Nanoreactors for the Synthesis of Polymers

9.3.2.1 Ring-Opening Polymerization

9.3.2.2 Controlled Radical Polymerization

9.3.3 Single-Chain Polymer Nanoparticles as Nanoreactors for the Synthesis of Nanomaterials

9.3.3.1 Gold Nanoparticles

9.3.3.2 Quantum Dots

9.3.3.3 Carbon Nanodots

9.4 Sensing

9.4.1 Single-Chain Polymer Nanoparticles as Sensors of Metal Ions

9.4.2 Single-Chain Polymer Nanoparticles as Sensors of Proteins

9.5 Other Uses

9.5.1 Porogens for Microelectronic Applications

9.5.2 Functional Nanoparticles for Bioscience.

9.5.3 Reversible Hydrogels.

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed September 16, 2017).

ISBN:

9783527806393

3527806393

9783527806386

3527806385

OCLC:

1001933457