Proteomics of Peroxisomes : Identifying Novel Functions and Regulatory Networks / edited by Luis A. del Río, Michael Schrader.

Format:

Book

Contributor:

del Río, Luis A., editor.

Schrader, Michael, editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Sub-cellular biochemistry 0306-0225 ; 89.

Subcellular Biochemistry, 0306-0225 ; 89

Language:

English

Subjects (All):

Proteomics.

Cytology.

Biochemistry.

Human genetics.

Cell physiology.

Cell Biology.

Animal Biochemistry.

Plant Biochemistry.

Human Genetics.

Cell Physiology.

Local Subjects:

Proteomics.

Cell Biology.

Animal Biochemistry.

Plant Biochemistry.

Human Genetics.

Cell Physiology.

Physical Description:

1 online resource (XIII, 493 pages) : 55 illustrations, 49 illustrations in color.

Edition:

First edition 2018.

Contained In:

Springer eBooks

Place of Publication:

Singapore : Springer Singapore : Imprint: Springer, 2018.

System Details:

text file PDF

Summary:

This new edited volume in the Springer Subcellular Biochemistry Series presents a comprehensive, state-of-the-art overview of the proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin, andcontains contributions from leading experts in the field. The development of sensitive proteomics and mass spectrometry technologies, combined with bioinformatics approaches now allow the identification of low-abundance and transient peroxisomal proteins and permits to identify the complete proteome of peroxisomes, with the consequent increase of our knowledge of the metabolic and regulatory networks of these important cellular organelles. The book lines-up with these developments and is organized in four sections including: (i) mass spectrometry-based organelle proteomics; (ii) prediction of peroxisomal proteomes; (iii) analysis of peroxisome proteome interaction networks; and (iv) peroxisomes in relation to other subcellular compartments. The editor Luis A. del Río is Professor ad honorem of the Spanish National Research Council (CSIC) in the Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Biochemistry and Cell and Molecular Biology of Plants, at the Estación Experimental del Zaidín, Granada, Spain. Del Río's research group focuses on the metabolism of reactive oxygen species (ROS), reactive nitrogen species (RNS) and antioxidants in plant peroxisomes, and the ROS- and RNS-dependent role of peroxisomes in plant cell signalling. The editor Michael Schrader is Professor of Cell Biology and Cytopathology in the Department of Biosciences at the University of Exeter, UK. Using mammalian peroxisomes as model organelles, Prof. Schrader and his team aim to unravel the molecular machinery and signalling pathways that mediate and regulate the formation, dynamics and abundance of these medically relevant cellular compartments.

Contents:

The proteome of plant peroxisomes

Defining the mammalian peroxisomal proteome

Fungal peroxisomes proteomics

The craft of peroxisome purification - a technical survey through the decades

Prediction of peroxisomal matrix proteins in plants

The obvious and the hidden: Prediction and function of fungal peroxisomal matrix proteins

Predicting peroxisomal targeting signals to elucidate the peroxisomal proteome of mammals

Multiple localization by functional translational readthrough

Evolution of the peroxisomal proteome

Peroxisome protein prediction in Drosophila melanogaster

Using Pull Down strategies to analyze the interactome of peroxisomal membrane proteins in human cells

Identification of peroxisomal protein complexes in mammalian cells

Unraveling of the structure and function of peroxisomal protein import machineries

The proteome of fruit peroxisomes: Sweet pepper (Capsicum annuum L.) as a model

Peroxisomes and their central role in metabolic interaction networks in humans

Characterisation of peroxisomal regulation networks

Multi-localized proteins: the peroxisome-mitochondria connection Peroxisome-mitochondria inter-relations in plants

Peroxisomes and cellular oxidant/antioxidant balance: protein redox

Cell death or survival against oxidative stress

A role for RNS in the communication of plant peroxisomes with other.

Other Format:

Printed edition:

ISBN:

978-981-13-2233-4

9789811322334

Access Restriction:

Restricted for use by site license.