Virus Infection and Tumorigenesis : Hints from Marine Hosts' Stress Responses / edited by Xiaobo Zhang.

Format:

Book

Contributor:

Zhang, Xiaobo, 1965- editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Language:

English

Subjects (All):

Oncology.

Medical virology.

Microbiology.

Zoology.

Cancer Research.

Virology.

Local Subjects:

Cancer Research.

Virology.

Microbiology.

Zoology.

Physical Description:

1 online resource (V, 318 pages) : 8 illustrations, 7 illustrations in color

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Singapore : Springer Singapore : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

This book reviews the latest research on the molecules and mechanisms of marine host stress responses to viral infections and tumorigenesis. It offers an overview of the state of the art in the field as well as future directions. Metabolism disorder is a characteristic of tumorigenesis. Since viruses complete their life cycle in host cells, such infections cause metabolic disorders in the host. As such, the mechanisms of virus pathogenesis and tumor progression are similar or even identical. In essence, the role of antiviral molecules is to maintain the metabolic homeostasis of infected host cells, and the antiviral molecules induced by virus infection may play an important role in antitumor pathways, resulting in cancer cell death or restoring the disordered metabolism of cancer cells. The molecules generated during host stress responses to viruses can also contribute to the antitumor mechanisms in humans. However, the relationship between host stress responses to virus infection and tumorigenesis has not been extensively explored. In recent years, studies have shown that marine host stress responses to viral invasion can be good models for exploring human antitumor mechanisms. Stimulating further research in the field, this book offers graduate students and researchers with comprehensive insights into host stress responses to viral invasion and tumor progression. It is also a valuable resource for those working in the pharmaceutical industry interested in drug discovery based on molecules derived from host stress responses to viral infection.

Contents:

Overview of virus infection and tumorigenesis

Marine viruses

Marine invertebrate stress responses to virus infection

The roles of microRNAs in antiviral immunity of marine invertebrates

Marine microbe stress responses to bacteriophage infection

Roles of microbial metabolites in bacteriophage-microbe interactions

Tumorigenesis and metabolism disorder

Effects of microRNAs from marine invertebrate stress responses to virus infection on tumorigenesis

Anti-tumor activities of secondary metabolites from marine microbe stress responses to virus infection.

Other Format:

Printed edition:

ISBN:

978-981-13-6198-2

9789811361982

Access Restriction:

Restricted for use by site license.