Escherichia coli, a Versatile Pathogen / edited by Gad Frankel, Eliora Z Ron.

Format:

Book

Contributor:

Frankel, Gad, editor.

Ron, Eliora Z., editor.

SpringerLink (Online service)

Series:

Biomedical and Life Sciences (Springer-11642)

Current topics in microbiology and immunology 0070-217X ; 416.

Current Topics in Microbiology and Immunology, 0070-217X ; 416

Language:

English

Subjects (All):

Microbiology.

Emerging infectious diseases.

Bacteriology.

Medical Microbiology.

Infectious Diseases.

Local Subjects:

Medical Microbiology.

Infectious Diseases.

Bacteriology.

Physical Description:

1 online resource (VII, 242 pages) : 40 illustrations, 20 illustrations in color.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2018.

System Details:

text file PDF

Summary:

Escherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection. This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.

Contents:

Shigella and enteroinvasive Escherichia coli

Enteroaggregative Escherichia coli

The Type III Secretion System of pathogenic Escherichia coli

Modulation of host cell processes by T3SS effectors

The 2011 German enterohemorrhagic Escherichia coli O104:H4 outbreak - the danger is still out there

Extraintestinal Pathogenic Escherichia coli

Pandemic bacteremic Escherichia coli strains: evolution and emergence of drug resistant pathogens

Current Trends in Antimicrobial Resistance of Escherichia coli

Vaccines against Escherichia coli.

Other Format:

Printed edition:

ISBN:

978-3-319-99664-6

9783319996646

Access Restriction:

Restricted for use by site license.