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Mechanisms of Drug Resistance in Cancer Therapy / edited by Mario Mandalà, Emanuela Romano.
Holman Biotech Commons QP905 .H3h v.50 (1978)-v.107 (1993), v.108 pt.2 (1993), v.110 (1994)-v.114 (1995), v.116 (1995)-v.122 (1996) v.124 (1997)-v.133 (1999), v.135 (1999)-v.163:1-2 (2004), v.164 (2004)-v.186 (2008) v.189 (2009),v.192 (2009)-v.195 (2010)v.199 (2010),v.201(2011)-v.217
Available
Levy Dental Medicine Library - Stacks QP905 .H3 v.127
Mixed Availability
- Format:
- Book
- Series:
- Biomedical and Life Sciences (Springer-11642)
- Handbook of experimental pharmacology 0171-2004 ; 249.
- Handbook of Experimental Pharmacology, 0171-2004 ; 249
- Language:
- English
- Subjects (All):
- Toxicology.
- Oncology.
- Drug interactions.
- Medicine.
- Pharmacology/Toxicology.
- Cancer Research.
- Drug Resistance.
- Molecular Medicine.
- Local Subjects:
- Pharmacology/Toxicology.
- Cancer Research.
- Drug Resistance.
- Molecular Medicine.
- Physical Description:
- 1 online resource (VIII, 297 pages) : 32 illustrations, 31 illustrations in color.
- Edition:
- First edition 2018.
- Contained In:
- Springer eBooks
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2018.
- System Details:
- text file PDF
- Summary:
- A major objective of this book is to reveal unprecedented opportunities to understand and overcome drug resistance through the clinical assessment of rational therapeutic drug combinations and the use of predictive and prognostic biomarkers to enable patient stratification and tailor treatments. It offers to the readers an updated overview on the possible reasons of failure of new and promising therapeutic opportunities.
- Contents:
- 1. Molecular and Pharmacological Mechanisms of Drug Resistance: An Evolving Paradigm
- 2. Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival
- 3. Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies
- 4. Mechanisms of Resistance to Target Therapies in Non-small Cell Lung Cancer
- 5. Mechanisms of Drug Resistance in Melanoma
- 6. Mechanisms of Resistance to Immune Checkpoint Antibodies
- 7. Immunotolerance as a Mechanism of Resistance to Targeted Therapies in Melanoma
- 8. Plasticity of Resistance and Sensitivity to Anti-Epidermal Growth Factor Receptor Inhibitors in Metastatic Colorectal Cancer
- 9. Targeting DNA repair
- 10. Resistance to Hormonal Therapy in Prostate Cancer
- 11. Mechanism of Resistance in Gastrointestinal Stromal Tumors
- 12. Mechanisms of Resistance to Targeted Therapies in Chronic Lymphocytic Leukemia
- 13. Mechanisms of Resistance to Targeted Therapies in Chronic Myeloid Leukemia
- 14. Mechanisms of Resistance in Multiple Myeloma
- 15. Cancer Evolution as the New Frontier of Precision.
- Other Format:
- Printed edition:
- ISBN:
- 978-3-030-10507-5
- 9783030105075
- Access Restriction:
- Restricted for use by site license.
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