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High-Throughput Metabolomics : Methods and Protocols / edited by Angelo D'Alessandro.
Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
Available
- Format:
- Book
- Series:
- Springer Protocols (Springer-12345)
- Methods in molecular biology 1064-3745 ; 1978.
- Methods in Molecular Biology, 1064-3745 ; 1978
- Language:
- English
- Subjects (All):
- Metabolism.
- Human genetics.
- Lipids.
- Bioinformatics.
- Metabolomics.
- Human Genetics.
- Lipidology.
- Computational Biology/Bioinformatics.
- Local Subjects:
- Metabolomics.
- Human Genetics.
- Lipidology.
- Computational Biology/Bioinformatics.
- Physical Description:
- 1 online resource (XV, 459 pages) : 83 illustrations, 63 illustrations in color.
- Edition:
- First edition 2019.
- Contained In:
- Springer eBooks
- Place of Publication:
- New York, NY : Springer New York : Imprint: Humana, 2019.
- System Details:
- text file PDF
- Summary:
- This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.
- Contents:
- Sample Preparation and Reporting Standards for Metabolomics of Adherent Mammalian Cells
- High-Throughput Metabolomics: Isocratic and Gradient Mass Spectrometry-Based Methods
- High-Throughput Metabolomics Based on Direct Mass Spectrometry Analysis in Biomedical Research
- Traveling Wave Ion Mobility Mass Spectrometry: Metabolomics Applications
- CE-MS for Metabolomics: A Comparison with Other Techniques
- Overview of Lipid Mass Spectrometry and Lipidomics
- LC-MS/MS-MRM-Based Targeted Metabolomics for Quantitative Analysis of Polyunsaturated Fatty Acids and Oxylipins
- Untargeted and Semi-Targeted Lipid Analysis of Biological Samples Using Mass Spectrometry-Based Metabolomics
- HPLC-MS/MS Methods for Diacylglycerol and Sphingolipid Molecular Species in Skeletal Muscle
- Quantification of D- and L-2-Hydroxyglutarate in Drosophila melanogaster Tissue Samples Using Gas Chromatography-Mass Spectrometry
- Comprehensive LC-MS-Based Metabolite Fingerprinting Approach for Plant and Fungal-Derived Samples
- Untargeted Metabolomics of Plant Leaf Tissues
- Analysis of Arginine Metabolism Using LC-MS and Isotopic Labeling
- Quantifying Intermediary Metabolism and Lipogenesis in Cultured Mammalian Cells Using Stable Isotope Tracing and Mass Spectrometry
- Insights into Dynamic Network States Using Metabolomic Data
- Analysis of Endothelial Fatty Acid Metabolism Using Tracer Metabolomics
- Using Stable Isotope Tracers for Metabolic Pathway Analysis
- Data Processing for GC-MS and LC-MS-Based Untargeted Metabolomics
- El-MAVEN: A Fast, Robust, and User-Friendly Mass Spectrometry Data Processing Engine for Metabolomics
- Pre-Analytic Considerations for Mass Spectrometry-Based Untargeted Metabolomics Data
- Temporal Metabolite, Ion, and Enzyme Activity Profiling Using Fluorescence Microscopy and Genetically-Encoded Biosensors
- Microplate Assays for Spectrophotometric Measurement of Mitochondrial Enzyme Activity
- Quantitative NMR-Based Metabolomics on Tissue Biomarkers and Its Translation into In Vivo Magnetic Resonance Spectroscopy
- Metabolomic Applications in Radiation Biodosimetry
- Metabolomics Analyses to Investigate the Role of Diet and Physical Training
- Blood Biomarkers in Sports Medicine and Performance and the Future of Metabolomics
- Personalized Metabolomics.
- Other Format:
- Printed edition:
- ISBN:
- 978-1-4939-9236-2
- 9781493992362
- Access Restriction:
- Restricted for use by site license.
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