Industrial process scale-up : a practical innovation guide from idea to commercial implementation / Jan Harmsen.

Format:

Book

Author/Creator:

Harmsen, Jan.

Series:

Gale eBooks

Language:

English

Subjects (All):

Manufacturing processes.

Physical Description:

1 online resource (viii, 116 pages) : illustrations (some color)

Edition:

1st edition

Place of Publication:

Oxford : Elsevier, 2013.

Language Note:

English

System Details:

text file

Summary:

This book will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels. The book can also be used in co-operation with industrial R&D people and academic researchers to shape open innovation programs and in education as a reference book for process innovation courses. <br><br><ul><br><ul></ul><li>Offers easily accessible, step-by-step, and concise guidelines for industrial process scale-up</li><li>Explains each st

Contents:

Front Cover; Industrial Process Scale-Up; Copyright Page; Dedication; Contents; Preface; Acknowledgement; 1 Introduction; 1.1 Purpose of the Book; 1.2 Scale-Up Definition; 1.3 Scale-Up Methodology; 1.4 Content Structure of the Book; 2 Process Industries Characteristics; 2.1 Industrial Players and Partners; 2.2 Supply and Value Chains; 2.2.1 Life Cycles; 2.3 Industrial Complexes; 2.4 Processes; 2.5 Unit Operations; 2.6 Major Process Equipment; 2.7 Transfer Phenomena; 2.8 Chemistry and Catalysis; 2.9 Types of Design in Innovation; 3 Ideation and Research Stages; 3.1 Ideation Stage

3.1.1 Sources of Ideas3.1.2 Early Technical Risk Assessment and the Role of Process Concept Design; 3.1.3 Early Stage Knowledge Gap Analysis and Risk Assessment; 3.1.4 Co-Operation with Innovation Partners; 3.1.5 Process Route Selection; 3.1.6 Ideation Stage-Gate Decision; 3.2 Research Stage; 3.2.1 Determining Potential Project Showstoppers; 3.2.2 Testing for Showstoppers; 3.2.3 Concept Design; 3.2.3.1 Role of Concept Design in Research Stage; 3.2.3.2 Guidelines; 3.2.3.2.1 Guidelines for Problem Definition; 3.2.3.2.2 Process Synthesis Hints; 3.2.3.3 Process Synthesis Design Using Functions

3.2.3.4 Reaction3.2.3.4.1 Reaction Cases with no By-Product Formation; 3.2.3.4.2 Reaction Cases with By-Product Formation by Consecutive Reactions; 3.2.3.4.3 Reaction Cases By-Products by Parallel Reactions; 3.2.3.4.4 Reaction Cases Specialty and Performance Products; 3.2.3.5 Separation; 3.2.3.6 Safe; 3.2.3.7 Socially Acceptable; 3.2.3.8 Low Cost; 3.2.3.9 Analysis; 3.2.3.10 Evaluation; 3.2.3.11 Reporting; 3.2.4 Role of Modelling and Simulation; 3.2.5 Essential Physical, Chemical and Thermodynamic Property Determination; 3.2.6 Research Stage-Gate Decision; 4 Development Stage

4.1 Mini-Plant Objectives and Design4.2 Pilot Plant Objectives and Design; 4.3 Cold-Flow Plant Objectives and Design; 4.4 Commercial Scale Process Design in Development Stage; 4.4.1 Design Base; 4.5 Development Gate Decision; 4.5.1 Risk Mitigation; 5 Demonstration Stage; 5.1 Rationale Demonstration Scale Process; 5.2 Execution Demonstration Stage; 6 Start-Up Commercial Processes; 6.1 Start-Up Time Prediction; 6.2 Start-Up Organisation; 6.2.1 Start-Up Leader; 6.2.2 Start-Up Team and Preparation; 6.3 Post-Start-Up Reporting; 7 Scale-Up of Unit Operations

7.1 Critical Success Factors for Unit Operations and Equipment7.2 Scale-Up Methods for Unit Operations; 7.2.1 Brute Force Scale-Up and Scale-Down Method; 7.2.2 Model-Based Scale-Up Method; 7.2.3 Empirical Scale-Up; 7.2.4 Empirical-Model Hybrid Scale-Up; 7.2.5 Direct Scale-Up; 7.3 Scale-Up of Most Used Unit Operations; 7.3.1 Adiabatic Fixed Bed Reactors; 7.3.1.1 Design of Fixed Bed Laboratory Reactors; 7.3.2 Space Velocity; 7.3.3 Catalyst Sample Representativeness; 7.3.4 Catalyst Loading; 7.3.5 Initial Feed Distribution; 7.3.6 Reactor Diameter; 7.3.7 Length of Catalyst Bed

7.3.8 Mass Transfer Limitations

Notes:

Description based upon print version of record.

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

ISBN:

9780444627391

0444627391

OCLC:

849932117