Huntington's disease / edited by Gillian Bates, Sarah Tabrizi and Lesley Jones ; Véronique M. André [and thirty seven others], contributors.

Format:

Book

Contributor:

Bates, Gillian, editor of compilation.

Tabrizi, Sarah, editor of compilation.

Jones, Lesley, 1957- editor of compilation.

André, Véronique M., contributor.

Series:

Oxford monographs on medical genetics.

Oxford Monographs on Medical Genetics

Standardized Title:

Huntington's disease (2014)

Language:

English

Subjects (All):

Huntington's disease.

Physical Description:

1 online resource (513 p.)

Edition:

Fourth edition.

Place of Publication:

New York : Oxford University Press, 2014.

Language Note:

English

Summary:

This fourth edition of Huntington's Disease presents a comprehensive summary of the current knowledge of this disease, including the major scientific and clinical advances that have occurred since publication of the third edition in 2002. Completely updated and expanded, chapters in this volume are organized in five sections: DT Clinical aspects of Huntington's disease, including updated chapters on historical perspectives, neurological, neuropsychiatric, and neuropsychological aspects, and new chapters on juvenile Huntington's and the premanifest and early stages DT The genetics of Huntington

Contents:

""Cover""; ""Huntington�s Disease""; ""Series""; ""Copyright""; ""Contents""; ""Contributors""; ""Section one Clinical Aspects of Huntington�s Disease""; ""1 Huntington�s Disease in a Historical Context""; ""2 Clinical Neurology""; ""3 Neuropsychiatry and Neuropsychology""; ""4 Juvenile Huntington�s Disease""; ""5 Premanifest and Early Huntington�s Disease""; ""Section two Genetics of Huntington�s Disease""; ""6 Genetic and Molecular Studies""; ""7 Epidemiology""; ""8 Genetic Counseling and Testing""; ""Section three Neurobiology of Huntington�s Disease""

""9 Neuropathology in the Human Brain""""10 Altered Neuronal Circuitry""; ""Section Four Molecular Biology of Huntington�s Disease""; ""11 Normal Function of Huntingtin""; ""12 Structural Biology: Order, Disorder, and Conformational Flux""; ""13 Pathogenic Mechanisms""; ""14 Peripheral Pathology""; ""Section five Therapeutic Interventions in Huntington�s Disease""; ""15 Comprehensive Care""; ""16 Preclinical Experimental Therapeutics""; ""17 Experimental Therapeutics: Moving Forward in Clinical Trials""; ""Index""

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

0-19-937047-8

0-19-937048-6

0-19-992915-7

OCLC:

874563137