Neuroblastoma : molecular mechanisms and therapeutic interventions / edited by Swapan K. Ray.

Format:

Book

Language:

English

Subjects (All):

Neuroblastoma.

Neuroblastoma--Treatment.

Genre:

Electronic books.

Physical Description:

1 online resource (x, 323 pages) : illustrations (some color)

Place of Publication:

London : Academic Press, an imprint of Elsevier, [2019]

System Details:

data file

Summary:

"Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions"--Publisher's description.

Contents:

Neuroblastoma pathology and classification

Role of genetic and epigenetic alterations in pathogenesis of neuroblastoma

Neuroblastoma molecular biology and promising therapeutic targets

The GD2-targeted immunotherapy of neuroblastoma

Targeting angiogenesis in neuroblastoma

Autophagy and novel therapeutic strategies in neuroblastoma

Energy metabolism and new therapeutic opportunities in neuroblastoma

Multimodality imaging for diagnosis of neuroblastoma

Immunotherapy for neuroblastoma

Advances in surgical treatment of neuroblastoma

Role of stemness factors in neuroblastoma: Neuroblastoma stem cells, tumor microenvironment, and chemoresistance

Current pharmacotherapy for neuroblastoma

Current challenges in the management of neuroblastoma

Novel therapeutic targets in neuroblastoma

Current and future strategies for treatment of relapsed neuroblastoma

Current evidence in favor of a tumor suppressor role of Krüppel-like factor 4 in malignant neuroblastoma

Modulation of expression of microRNA as a therapeutic strategy in malignant neuroblastoma.

Notes:

Includes bibliographical references and index.

Description based on online resource; title from resource home page (ClinicalKey, viewed March 14, 2019).

Other Format:

Print version: Neuroblastoma.

ISBN:

9780128120040

0128120045

OCLC:

1082875314

Access Restriction:

Restricted for use by site license.