Multi-Target Drug Design Using Chem-Bioinformatic Approaches / edited by Kunal Roy.

Format:

Book

Contributor:

Roy, Kunal, 1971- editor.

SpringerLink (Online service)

Series:

Springer Protocols (Springer-12345)

Methods in pharmacology and toxicology 1557-2153

Methods in Pharmacology and Toxicology, 1557-2153

Language:

English

Subjects (All):

Toxicology.

Pharmacology/Toxicology.

Local Subjects:

Pharmacology/Toxicology.

Physical Description:

1 online resource (XVI, 563 pages) : 100 illustrations, 90 illustrations in color.

Contained In:

Springer eBooks

Place of Publication:

New York, NY : Springer New York : Imprint: Humana Press, 2019.

System Details:

text file PDF

Summary:

This detailed book showcases recent advances in computational design of multi-target drug candidates involving various ligand and structure-based strategies. Different chem-bioinformatic modeling strategies that can be applied for design of multi-target drugs as well as important databases and web servers in connection with multi-target drug design are also featured in this collection. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of key implementation advice that will aid researchers greatly in their laboratory pursuits. Authoritative and practical, Multi-Target Drug Design Using Chem-Bioinformatic Approaches seeks to aid all scientists working in the field of drug discovery research.

Contents:

Cheminformatics Approaches to Study Drug Polypharmacology

Computational Predictions for Multi-Target Drug Design

Computational Multi-Target Drug Design

Multi-Target Drug Design for Neurodegenerative Diseases

Molecular Docking Studies in Multi-Target Antitubercular Drug Discovery

Advanced Chemometric Modeling Approaches for the Design of Multi-Target Drugs against Neurodegenerative Diseases

Computational Studies on Natural Products for the Development of Multi-Target Drugs

Computational Design of Multi-Target Drugs against Alzheimer's Disease

Design of Multi-Target Directed Ligands as a Modern Approach for the Development of Innovative Drug Candidates for Alzheimer's Disease

Virtual Screening for Dual Hsp90/B-Raf Inhibitors

Strategies for Multi-Target Directed Ligands: Application in Alzheimer's Disease (AD) Therapeutics

Computational Design of Multi-Target Kinase Inhibitors

Proteochemometrics for the Prediction of Peptide Binding to Multiple HLA Class II Proteins

Linked Open Data: Ligand-Transporter Interaction Profiling and Beyond

Design of Novel Dual Target Hits against Malaria and Tuberculosis Using Computational Docking

Computational Design of Multi-Target Drugs against Breast Cancer

Computational Methods for Multi-Target Drug Designing against Mycobacterium tuberculosis

Development of a Web-Server for Identification of Common Lead Molecules for Multiple Protein Targets

Computational Method for Prediction of Targets for Breast Cancer Using siRNAs Approach

Historeceptomics: Integrating a Drug's Multiple Targets (Polypharmacology) with Their Expression Pattern in Human Tissues

Networking of Smart Drugs: A Chem-Bioinformatic Approach to Cancer Treatment.

Other Format:

Printed edition:

ISBN:

9781493987337

Access Restriction:

Restricted for use by site license.