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Microbial Metabolomics : Methods and Protocols / edited by Edward E.K. Baidoo.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Baidoo, Edward E. K., editor.
SpringerLink (Online service)
Series:
Springer Protocols (Springer-12345)
Methods in molecular biology 1064-3745 ; 1859.
Methods in Molecular Biology, 1064-3745 ; 1859
Language:
English
Subjects (All):
Microbiology.
Local Subjects:
Microbiology.
Physical Description:
1 online resource (X, 351 pages) : 83 illustrations, 50 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana Press, 2019.
System Details:
text file PDF
Summary:
This detailed volume includes protocols that represent the breadth of microbial metabolomics approaches to both large-scale and small-scale experiments with intention of highlighting techniques that can be used for applications ranging from environmental microbiology to human disease. Utilizing mass spectrometry as their primary measurement tool, the chapters explore microbial metabolomics, metabolism and microbial physiology, metabolite sample preparation, current analytical techniques used to profile primary and secondary metabolites and lipids, as well as establishing data analysis workflows for targeted metabolomics, untargeted metabolomics, analysis of metabolic fluxes, and genome-scale models. Written for the highly successful Methods in Molecular Biology series, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Microbial Metabolomics: Methods and Protocols serves as an ideal reference for both novice and advanced users and can be adapted to similar analytical platforms or customized to suit the needs of the researcher.
Contents:
Microbial Metabolomics: A General Overview
Mass Spectrometry-Based Microbial Metabolomics: Techniques, Analysis, and Applications
Metabolomics: A Microbial Physiology and Metabolism Perspective
Untargeted Soil Metabolomics Using Liquid Chromatography-Mass Spectrometry and Gas Chromatography-Mass Spectrometry
Fatty Acid Metabolome Extraction from Mycobacterial Cells for GC-MS Metabolomics Analysis
Total Metabolome Extraction from Mycobacterial Cells for GC-MS Metabolomics Analysis
High-Throughput Solid Phase Microextraction-Liquid Chromatography-Mass Spectrometry for Microbial Untargeted Metabolomics
Targeted Metabolomics of Xylose Fermenting Yeasts Based on Mass Spectrometry
Exploiting High-Resolution Mass Spectrometry for Targeted Metabolite Quantification and 13C-labeling Metabolism Analysis
Quantitative Profiling of Endogenous Metabolites Using Hydrophilic Inter-Action Liquid Chromatography-Tandem Mass Spectrometry (HILIC-MS/MS)
Liquid Chromatography and Mass Spectrometry Analysis of Isoprenoid Intermediates in Escherichia coli
Determining the Mode of Action of Antimalarial Drugs Using Time-Resolved LC-MS-Based Metabolite Profiling
Use of Liquid Chromatography-Mass Spectrometry-Based Metabolomics to Identify Biomarkers of Tuberculosis
Metabolomics Analysis of Leishmania by Capillary Electrophoresis and Mass Spectrometry
A High-Throughput Targeted Metabolomics Workflow for the Detection of 200 Polar Metabolites in Central Carbon Metabolism
Cluster Analysis of Untargeted Metabolomic Experiments
Machine Learning in Untargeted Metabolomics Experiments
Dynamic 13C Labeling of Fast Turnover Metabolites for Analysis of Metabolic Fluxes and Metabolite Channeling
Genome-Scale 13C Fluxomics Modeling for Metabolic Engineering of Saccharomyces cerevisiae.
Other Format:
Printed edition:
ISBN:
9781493987573
Access Restriction:
Restricted for use by site license.

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