Toxicology of nanomaterials / edited by Yuliang Zhao, Zhiyong Zhang, and Weiyue Feng.

Format:

Book

Contributor:

Zhao, Yuliang, editor.

Zhang, Zhiyong, editor.

Feng, Weiyue, editor.

Language:

English

Subjects (All):

Nanostructured materials--Toxicology.

Nanostructured materials.

Physical Description:

1 online resource (435 p.)

Edition:

1st ed.

Place of Publication:

Weinheim, Germany : Wiley-Vch Verlag GmbH & Co. KGaA, 2016.

Summary:

This book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.

Contents:

Cover; Title Page; Copyright; Contents; List of Contributors; Preface; Abbreviations; Chapter 1 Characterization of Nanomaterials in Nanotoxicological Analyses; 1.1 Introduction; 1.2 Size and Morphology of NMs; 1.2.1 Transmission Electron Microscopy (TEM); 1.2.2 Scanning Electron Microscopy (SEM); 1.2.3 Scanning Tunneling Microscopy (STM); 1.2.4 Atomic Force Microscopy (AFM); 1.2.5 Dynamic Light Scattering (DLS); 1.2.6 X-ray Diffraction (XRD); 1.2.7 Small-Angle X-ray Scattering (SAXS); 1.2.8 Brunauer-Emmett-Teller (BET); 1.2.9 Raman Scattering (RS); 1.3 Composition and Structure

1.3.1 Absorption and Emission Spectroscopy1.3.2 Mass Spectrometry (MS); 1.3.3 X-ray Fluorescence Spectrometry (XRF); 1.3.4 Nuclear Magnetic Resonance (NMR); 1.3.5 X-ray Absorption Spectroscopy (XAS); 1.4 Surface Properties; 1.4.1 Surface Area; 1.4.2 Surface Charge; 1.4.3 Surface Composition; 1.4.4 Surface Reactivity; 1.5 Interactions between NMs and Biological Environments; 1.6 Conclusions; References; Chapter 2 Quantitative Analysis of Metal-Based Nanomaterials in Biological Samples Using ICP-MS; 2.1 Introduction; 2.2 ICP-MS: A Power Tool for Element Analysis; 2.2.1 Unique Features of ICP-MS

2.2.2 ICP-MS Hyphenated to Separation Techniques2.3 Single-Particle ICP-MS: Theory and Application; 2.3.1 Basic Theory of SP-ICP-MS; 2.3.2 Applications of SP-ICP-MS; 2.4 Analysis of Nanoparticles by ICP-MS Hyphenate Techniques; 2.4.1 Solution-Based ICP-MS Hyphenated Techniques; 2.4.1.1 Field Flow Fractionation; 2.4.1.2 Hydrodynamic Chromatography; 2.4.1.3 Electrophoresis; 2.4.1.4 Laser Ablation ICP-MS for ENM Analysis; 2.5 Conclusion and Outlook; References; Chapter 3 Stable Isotopic Tracing of Nanomaterials In Vivo; 3.1 Introduction

3.2 Development of Stable Isotope Labeling in Nanotechnology3.3 13C-Labeled Carbon Nanomaterials; 3.3.1 Structure and Formation Mechanisms for Fullerene; 3.3.2 Trace and Quantification In Vivo for Fullerene; 3.3.3 Quantification and Distribution of 13C-CNT and Carbon Particles; 3.3.4 Isotope Effects and Imaging of 13C-CNT; 3.3.5 Structure and Formation of 13C-Enriched Graphene Nanomaterials; 3.4 Metal Stable Isotope Labeled Nanoparticles; 3.4.1 Trace and Quantification of ZnO Nanoparticles in Nanotoxicology and Ecotoxicology

3.4.2 Trace and Quantification of CuO Nanoparticles in Nanotoxicology and Ecotoxicology3.4.3 Other Stable Isotopes for Tracing and Quantifying Nanomaterials In Vivo; 3.4.4 Other Stable Isotopes for the Structure and Reaction of Nanomaterials; 3.5 Summary and Outlook; References; Chapter 4 Radiolabeling of Nanoparticles; 4.1 Introduction; 4.1.1 Radioisotope Production; 4.1.2 Radiolabeling Methods of Nanoparticles; 4.1.2.1 Synthesis of Nanoparticles from Radioactive Precursors; 4.1.2.2 Neutron or Ion-Beam Activation; 4.1.2.3 Isotopic Exchange and Cation Exchange; 4.1.2.4 Physical Absorption

4.1.2.5 Covalent Attachment

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (ebrary, viewed September 15, 2016).

ISBN:

9783527689156

352768915X

9783527689132

3527689133

9783527689125

3527689125

OCLC:

957683832