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Translational medicine : tools and techniques / edited by Aamir Shahzad, president, European Society for Translational Medicine (EUSTM), Vienna, Austria, School of Medicine University of Colorado, Aurora, CO, USA.
- Format:
- Book
- Language:
- English
- Subjects (All):
- Medicine--Research.
- Medicine.
- Medicine, Experimental.
- Human experimentation in medicine.
- Biology--Research.
- Biology.
- Physical Description:
- 1 online resource (198 p.)
- Edition:
- 1st ed.
- Place of Publication:
- Amsterdam : Elsevier, [2016]
- Language Note:
- English
- Summary:
- Translational Medicine: Tools and Techniques provides a standardized path from basic research to the clinic and brings together various policy and practice issues to simplify the broad interdisciplinary field. With discussions from academic and industry leaders at international institutions who have successfully implemented translational medicine.
- Contents:
- Front Cover; TRANSLATIONAL MEDICINE: TOOLS AND TECHNIQUES; Copyright; Contents; List of Contributors; About the Editor; Preface; Acknowledgments; 1 - New Developments in the Use of Biomarkers in Translational Medicine; INTRODUCTION; BIOMARKERS AS PART OF A TRANSLATIONAL STRATEGY; NEW TYPES OF BIOMARKERS; From Blood- to Tissue-Specific Biomarkers; From Static to Functional Biomarker Assays; From Static Ex Vivo Monitoring to In Vivo Continuous Imaging; From Single Protein Molecules to Nonbiochemical Biomarkers; NEW WAYS OF ANALYZING BIOMARKER DATA; From Single Biomarkers to Biomarker Patterns
- Modeling in Target Identification and ValidationModeling in Lead Identification and Optimization; Modeling in ADME; Use of Modeling and Simulation in Phase 1; Modeling and Simulation in Phases 2, 3, and 4; Impact of Modeling and Simulation on Drug Approvals; Oncology, a Special Case; NEXT LEVEL OF CONTRIBUTION FROM MODELING AND SIMULATION; References; 4 - Advancements in Omics Sciences; OUTLINE OF THE CHAPTER; INTRODUCTION; GENOMICS; Genomic Technologies; Microarrays; Quantitative PCR; Next-Generation Sequencing; Array-Based Comparative Genome Hybridization; Genome-Wide Association Studies
- Clinical Biomarkers
- Notes:
- Description based upon print version of record.
- Includes bibliographical references and index.
- Description based on online resource; title from PDF title page (ebrary, viewed December 31, 2015).
- Description based on publisher supplied metadata and other sources.
- ISBN:
- 9780128034941
- 0128034947
- OCLC:
- 932333863
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