Moonlighting proteins : novel virulence factors in bacterial infections / edited by Brian Henderson.

Format:

Book

Contributor:

Henderson, Brian (Professor), editor.

Language:

English

Subjects (All):

Bacterial diseases.

Physical Description:

1 online resource (529 pages) : illustrations (some color), tables

Edition:

1st ed.

Place of Publication:

Chichester, West Sussex, England : Wiley Blackwell, 2017.

Summary:

Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections is a complete examination of the ways in which proteins with more than one unique biological action are able to serve as virulence factors in different bacteria. The book explores the pathogenicity of bacterial moonlighting proteins, demonstrating the plasticity of protein evolution as it relates to protein function and to bacterial communication. Highlighting the latest discoveries in the field, it details the approximately 70 known bacterial proteins with a moonlighting function related to a virulence phenomenon. Chapters describe the ways in which each moonlighting protein can function as such for a variety of bacterial pathogens and how individual bacteria can use more than one moonlighting protein as a virulence factor. The cutting-edge research contained here offers important insights into many topics, from bacterial colonization, virulence, and antibiotic resistance, to protein structure and the therapeutic potential of moonlighting proteins. Moonlighting Proteins: Novel Virulence Factors in Bacterial Infections will be of interest to researchers and graduate students in microbiology (specifically bacteriology), immunology, cell and molecular biology, biochemistry, pathology, and protein science.

Contents:

What is protein moonlighting and why is it important? / Constance J. Jeffery

Exploring structure-function relationships in moonlighting proteins / Sayoni Das, Ishita Khan, Daisuke Kihara, Christine Orengo

Overview of protein moonlighting in bacterial virulence / Brian Henderson

Moonlighting proteins as cross-reactive autoantigens / Wim van Eden

Chaperonin 60 paralogues in mycobacterium tuberculosis and tubercle formation / Brian Henderson

Legionella pneumophila chaperonin 60 an extra- and intra-cellular moonlighting virulence-related factor / Karla N. Valenzuela-Valderas, Angela L. Riveroll, Peter Robertson, Lois E. Murray, and Rafael A. Garduño

An overview of peptidylprolyl isomerases in bacterial virulence / Brian Henderson

GAPDH : a multifunctional moonlighting protein in eukaryotes and prokaryotes / Michael A. Sirover

Streptococcus pyogenes GAPDH : a cell surface major virulence determinant / Vijay Pancholi

Group B streptococcus GAPDH and immune evasion / Paula Ferreira and Patrick Trieu-Cuot

Mycobacterium tuberculosis cell surface gapdh functions as a transferrin receptor / Vishant M Borradia, Manoj Raje, Chaaya Iyengar

Gapdh and probiotic organisms / Hideki Kinoshita

Impact of streptococcal enolase in virulence / Marcus Fulde and Simone Bergmann

Streptococcal enolase and immune evasion / Masaya Yamaguchi and Shigetada Kawabata

Borrelia burgdorferi enolase and plasminogen binding / Catherine A. Brissette

Triosephosphate isomerase from staphylococcus aureus and plasminogen receptors on microbial pathogens / Reiko Ikeda, Tomoe Ichikawa

Moonlighting functions of bacterial fructose-1,6 bisphosphate-aldolases / Neil J Oldfield, Fariza Shams, Karl G Wooldridge and David PJ Turner

Pyruvate dehydrogenase and plasminogen binding in mycoplasmas / Anne Gründel, Kathleen Friedrich, Melanie Pfeiffer, Enno Jacobs, Roger Dumke

Unexpected interactions of leptospiral ef-tu proteins / Natalia Salazar and Angela Barbosa

Mycobacterium tuberculosis antigen 85 family proteins : mycolyl transferases and matrix-binding adhesins / Christopher P. Ptak, Chih-Jung Kuo, and Yung-Fu Chang

Miscellaneous il-1[beta]-binding proteins of aggregatibacter actinomycetemcomitans / Riikka Ihalin

Bacteriophage moonlighting in the control of bacterial pathogenicity / Janine Bowring, Alberto Marina, José R. Penadés and Nuria Quiles-Puchalt

Viral entry glycoproteins and viral immune evasion / Jonathan D. Cook and Jeffrey E. Lee.

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781118951132

1118951131

9781118951125

1118951123

9781118951149

111895114X

OCLC:

962172160