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Human reproductive and prenatal genetics / edited by Peter C.K. Leung, Jie Qiao.

Elsevier ScienceDirect eBook - Biochemistry, Genetics and Molecular Biology 2018 Available online

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Format:
Book
Contributor:
Leung, P. C. K., editor.
Qiao, Jie, 1964- editor.
Language:
English
Subjects (All):
Human reproductive technology.
Human reproduction.
Genitalia--embryology.
Gametogenesis |x genetics.
Reproductive Techniques, Assisted.
Preimplantation Diagnosis |x methods.
Reproduction.
Medical Subjects:
Genitalia--embryology.
Gametogenesis |x genetics.
Reproductive Techniques, Assisted.
Preimplantation Diagnosis |x methods.
Reproduction.
Physical Description:
1 online resource (xv, 693 pages) : illustrations (chiefly color)
Place of Publication:
London : Academic Press, an imprint of Elsevier, [2019]
Summary:
Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available.
Contents:
Part I: Reproductive tract development and gametogenesis. Developmental genetics of the male reproductive system
Genetics and genomics of early gonad development
Genetics of meiotic chromosome dynamics and fertility
Effects of aging on sperm chromatin
In vitro spermatogenesis from pluripotent stem cells
Developmental genetics of the female reproductive tract
The molecular genetics of oogenesis
Epigenetic control of oocyte development
RNA binding protein networks and translational regulation in oocytes
Translational regulation of gene expression during oogenesis and preimplantation embryo development
MicroRNAs in gametes and preimplantation embryos: clinical implications
Part II: Embryo implantation, placenta development and pregnancy. Transcriptomics of the human endometrium and embryo implantation
Epigenetic modifications in the human placenta
MicroRNAs in pregnancy: implications for basic research and clinical management
Genetics and genomics of preterm birth
The intergenerational effects on fetal programming
Part III: Infertility and assisted reproductive technology . Genetic testing in male infertility
Genetics and genomics of endometriosis☆
Genetics and genomics of primary ovarian insufficiency
Genetics of polycystic ovary syndrome
Genetics and genomics of recurrent pregnancy loss
Human genetics and assisted reproduction in endometriosis
Uterine transplantation
Part IV: Preimplantation/prenatal genetic diagnosis and screening. Epidemiology and genetics of human aneuploidy
Next-generation sequencing for gene panels and clinical exomes
Chromosomal microarrays and exome sequencing for diagnosis of fetal abnormalities
Noninvasive prenatal testing for genetic diseases
Noninvasive prenatal testing by cell-free DNA: technology, biology, clinical utility, and limitations
Prenatal diagnosis and treatment of genetic steroid disorders
Application of gene-editing technologies in embryos and their potential for gene therapy.
Notes:
Includes bibliographical references and index.
Online resource; title from resource home page (ScienceDirect, viewed January 8, 2020).
Other Format:
Print version: Human reproductive and prenatal genetics.
ISBN:
9780128135716
0128135719
OCLC:
1050437363
Access Restriction:
Restricted for use by site license.

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