Principles and practice of clinical electrophysiology of vision / editors, John R. Heckenlively and Geoffrey B. Arden ; associate editors, Steven Nusinowitz, Graham E. Holder, Michael Bach.

Format:

Book

Contributor:

Heckenlively, John R.

Arden, Geoffrey B. (Geoffrey Bernard)

Language:

English

Subjects (All):

Electroretinography.

Electrooculography.

Visual evoked response.

Physical Description:

xxii, 977 p., [32] p. of plates : ill. (some col.).

Edition:

2nd ed.

Place of Publication:

Cambridge, Mass. : MIT Press, c2006.

Language Note:

English

Summary:

The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information--important material that is likely to become more important in the next decade--but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

Contents:

1 History of the electroretinogram

2 History of electro-oculography

3 History of visual evoked cortical testing

4 The photoreceptor-retinal pigment epithelium interface

5 Membrane mechanisms of the retinal pigment epithelium

6 Functional organization of the retina

7 Phototransduction and photoreceptor physiology

8 Synaptic transmission: sensitivity control mechanisms

9 Structure and function of retinal synapses: role of cell adhesion molecules and extracellular matrix

10 Central disorders of vision in humans

11 Origin and significance of the electro-oculogram

12 Origin of the electroretinogram

13 Origin of the pattern electroretinogram

14 Multifocal electroretinographic and visual evoked potential techniques

15 Origin of the visual evoked potentials

16 Data acquisition systems for electrodiagnostic testing

17 Electrodes for visual testing

18 Amplifiers and special-purpose data acquisition systems

19 Stimulus devices, calibration, and measurement of light

20 Introduction to the ISCEV standards

EOG standard

Standard for clinical electroretinography

Visual evoked potentials standard

Guidelines for basic multifocal electroretinography

21 Multifocal techniques

22 Pattern electroretinogram

23 Assessing infant acuity, fusion, and stereopsis with visual evoked potentials

24 Aging and pattern visual evoked cortical potential

25 Aberrant albino and achiasmat visual pathways: noninvasive electrophysiological assessment

26 Clinical psychophysical techniques

27 Measurement of contrast sensitivity

28 Suppressive rod-cone interaction

29 Use of fluorescein angiography as an adjunct to electrophysiological testing

30 Experimental design and data analyses in vision function testing

31 Analytical techniques

32 Reverse correlation methods

33 Stimulus-response functions for the scotopic b-wave

34 Kernel analysis

35 Measuring the health of the human photoreceptors with the leading edge of the a-wave

36 Localizing lesions in the visual system

37 Paired-flash ERG analysis of rod phototransduction and adaptation

38 Hyperabnormal (supranormal) electroretinographic responses

39 Technical issues in evaluating patients for therapeutic trials

40 Early receptor potential

41 Nonphotic standing potential responses: hyperosmolarity, bicarbonate, and diamox responses

42 Direct current electroretinogram

43 Oscillatory potentials of the electroretinogram

44 Flicker electroretinography

45 Chromatic recordings of electroretinograms

46 Adaptation effects on the electroretinogram

47 Clinical electrophysiological and psychophysical investigations into color defects

48 Causes and cures of artifacts

49 Testing levels of the visual system

50 Effects of high myopia on the electroretinogram

51 Electrodiagnostic testing in malingering and hysteria

52 Developmental amblyopia

53 Visual evoked potentials in cortical blindness

54 Drug side effects and toxicology of the visual system

55 Mitochondrial diseases

56 Diseases of the middle retina: venous and arterial occlusions

57 Acute disorders of the outer retina, pigment epithelium and choroid

58 Autoimmune retinopathy, CAR and MAR syndromes

59 Ischemic optic neuropathy

60 Gyrate atrophy of the choroid and retina

61 Dominant drusen

62 Stargardt disease

63 Bietti's crystalline dystrophy of the cornea and retina

64 Lever congenital amaurosis

65 Pattern dystrophies

66 Best vitelliform macular dystrophy

67 Sorsby's fundus dystrophy

68 Choroideremia

69 Retinitis pigmentosa

70 Cone dystrophies and degenerations

71 Vitamin A deficiency

72 Differential diagnosis of the electronegative electroretinogram

73 Juvenile x-linked retinoschisis

74 Congenital stationary night blindness

75 Quinine retinopathy

76 Leber's hereditary optic neuropathy

77 Pattern electroretinogram in glaucoma and ocular hypertension

78 Chiasmal and retrochiasmal lesions

79 Optic nerve and central nervous dysfunctions: Parkinson's disease and multiple sclerosis

80 r Diseases of fatty acid storage and metabolism: neuronal ceroid lipofuscinoses and the long-chain 3-Hydroxyacyl-CoA dehydrogenase deficiency

81 Evaluating retinal function in the mouse retina with the electroretinogram

82 Electroretinograms of dog and chicken

83 Electroretinographic testing in larger animals

84 Visual evoked potentials in animals.

Notes:

Bibliographic Level Mode of Issuance: Monograph

OCLC-licensed vendor bibliographic record.

Includes bibliographical references and index.

ISBN:

0-262-31155-0

1-282-09822-5

9786612098222

0-262-27518-X

1-4237-8415-4

OCLC:

70201691