Seldin and Giebisch's the kidney : physiology and pathophysiology / [edited by] Robert J. Alpern, Orson W. Moe, Michael Caplan.

Format:

Book

Contributor:

Alpern, Robert J., editor.

Moe, Orson W., editor.

Caplan, Michael, editor.

Language:

English

Subjects (All):

Kidneys--Physiology.

Kidneys.

Kidneys--Pathophysiology.

Kidneys--Diseases.

Water-Electrolyte Balance.

Water-Electrolyte Imbalance.

Kidney Diseases--physiopathology.

Kidney--physiology.

Medical Subjects:

Water-Electrolyte Balance.

Water-Electrolyte Imbalance.

Kidney Diseases--physiopathology.

Kidney--physiology.

Genre:

Electronic books.

Physical Description:

1 online resource (2 volume (xix, 3278 pages)) : illustrations (some color)

Edition:

FIfth edition.

Other Title:

Kidney

Place of Publication:

London : Elsevier/Academic Press, 2013.

System Details:

data file

Summary:

A classic nephrology reference for over 25 years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters.Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions.

Contents:

V. 1. I. Epithelial and nonepithelial transport and regulation. Epithelial cell structure and polarity / Karl S. Matlin and Michael J. Caplan

Mechanisms of ion transport across cell membranes / Luis Reuss and Guillermo A. Altenberg

Renal ion-translocating ATPases / Dominique Eladari, Udo Hasler and Eric Féraille

Mechanisms of water transport across cell membranes and epithelia / Guillermo a. altenberg and Luis Reuss

Cell volume control / Florian Lang

Solute transport, energy consumption, and production in the kidney / Takashi Sekine and Hitoshi Endou

Electrophysiological analysis of transepithelial transport / Henry Sackin and Lawrence G. Palmer

Renal ion channels, electrophysiology of transport, and channelopathies / James D. Stockand

Microvascular permeability and the exchange of water and solutes across microvascular walls / C. Charles Michel

External balance of electrolytes and acids and alkali / Man S. Oh

Renal cilia structure, function, and physiology / Jay N. Pieczynski and Bradley K. Yoder

Intercellular junctions / Alan S.L. Yu, Fiona Hanner and János Peti-Peterdi

Principles of cell signaling / Lloyd Cantley

Scaffolding proteins in transport regulation / Paul A. Welling

The renin-angiotensin system / Thu H. Le ... [et al.]

Neural control of renal function / Edward J. Johns and Ulla C. Kopp

Eicosanoids and renal function / Matthew D. Breyer, Raymond C. Harris and Richard M. Breyer

Extracellular nucleotides and renal function / David G. Shirley ... [et al.]

Paracrine regulation of renal function by dopamine / Pedro A. Jose, Robin A. Felder and Gilbert M. Eisner

II. Structural and functional organization of the kidney. Structural organization of the mammalian kidney / Wilhelm Kriz and Brigitte Kaissling

Biophysical basis of glomerular filtration / Scott C. Thomson and Roland C. Blantz

Glomerular cell biology / Yoshiro Maezawa, Davide Cina and Susan E. Quaggin

Function of the juxtaglomerular apparatus: control of glomerular hemodynamics and renin secretion / Jürgen B. Schnermann and Hayo Castrop

Renal cortical and medullary microcirculations: structure and function / Thomas L. Pallone and Chunhua Cao

Molecular and cellular mechanisms of kidney development / Kevin T. Bush, Hiroyuki Sakurai and Sanjay K. Nigam

Molecular and cellular mechanisms of glomerular capillary development / Jeffrey H. Miner and Dale R. Abrahamson

Postnatal renal development / Michel Baum, Jyothsna Gattineni and Lisa M. Satlin

Renal hyperplasia and hypertrophy / Paul T. Brinkkoetter, Sian V. Griffin and Stuart J. Shankland

Stem cells and generation of new cells in the adult kidney / Juan A. Oliver and Qais Al-Awqati

III. Fluid and electrolyte regulation and dysregulation. Epithelial Na+ channels / Shaohu Sheno, Kenneth R. Hallows and Thomas R. Kleyman

Anion channels / Owen M. Woodward and William B. Guggino

Physiology and pathophysiology of the NaCl co-transporters in the kidney / Gerardo Gamba

Sodium and chloride transport: proximal nephron / Alan M. Weinstein

Sodium chloride transport in the loop of Henle, distal convoluted tubule, and collecting duct / Gerardo Gamba, Wenhui Wang and Laurent Schild

Mineralocorticoid action in the aldosterone sensitive distal nephron / Oliver Staub and Johannes Loffing

Inherited disorders of renal salt homeostasis: insights from molecular genetics studies / Ute I. Scholl and Richard P. Lifton

Natriuretic hormones / David L. Vesely

Pathophysiology of sodium retentiona nd wastage / Biff F. Palmer, Robert J. Alpern and Donald W. Seldin

Physiology and pathophysiology of hypertension / John E. Hall, Joey P. Granger and Michael E. Hall

Physiology and pathophysiology of diuretic action / David H. Ellison

Aquaporin water channels in mammalian kidney / Søren Nielsen ... [et al.]

Thirst and vasopressin / Gary L. Robertson

The urine concentrating mechanism and urea transporters / Jeff M. Sands and Harold E. Layton

Hyponatremia / Richard H. Sterns, Stephen M. Silver and J. Kevin Hix

Hypernatremic states / Christopher J. Rivard, Wei Wang and Laurence Chan

Polyuria and diabetes insipidus / Daniel G. Bichet

The molecular biology of renal K+ channels / Wenhui Wang and Chou-Long Huang

Extrarenal potassium metabolism / Vaibhav Sahni, Aleksandra Gmurczyk and Robert M. Rosa

Regulation of K+ excretion / Gerhard Malnic ... [et al.]

Physiopathology of potassium deficiency / Francesco Trepiccione, Miriam Zacchia and Giovambattista Capasso

V. 2. Clinical disorders of hyperkalemia / Kamel S. Kamel ... [et al.]

Control of intracellular pH / Mark O. Bevensee and Walter F. Boron

SLC4 sodium-driven bicarbonate transporters / Ira Kurtz

The SLC4 anion exchanger gene family / Andrew K. Stewart and Seth L. Alper

Cellular mechanisms of renal tubular acidification / L. Lee Hamm, Robert J. alpern and Patricia A. Preisig

Chemoreceptors, breathing and pH / Eugene Nattie

Renal ammonium ion production and excretion / Norman P. Curthoys

Clinical syndromes of metabolic alkalosis / Orson W. Moe, Robert J. Alpern and Donald W. Seldin

Clinical syndromes of metabolic acidosis / Reto Krapf, Donald W. Seldin and Robert J. Alpern

Respiratory acid-base disorders / Nicolaos E. Madias and Horacio J. Adrogue

Mechanisms and disorders of magnesium metabolism / Karl P. Schlingmann, Gary A. Quamme and Martin Konrad

Calcium channels / Joost G.J. Hoenderop and René J.M. Bindels

The calcium-sensing receptor / Edward M. Brown ... [et al.]

Renal calcium metabolism / José F. Bernardo and Peter A. Friedman

The hormonal regulation of calcium metabolism / Peter J. Tebben and Rajiv Kumar

Disorders of calcium metabolism / Cristina Dumitru and John Wysolmerski

Pathogenesis and treatment of nephrolithiasis / Fredric L. Coe, Andrew Evan and Elaine Worcester

Proximal tubular handling of phosphate / Heini Murer ... [et al.]

Clinical disturbances of phosphate homeostasis / Theresa J. Berndt and Rajiv Kumar

Glucose reabsorption in the kidney / Charles S. Hummel and Ernest M. Wright

Kidney transport of amino acids and oligopeptides, and aminoacidurias / Simone M.R. Camargo ... [et al.]

Organic anion and cation transporters in renal elimination of drugs / Gerhard Burckhardt and Hermann Koepsell

Renal filtration, transport, and metabolism of albumin and albuminuria / Erik Ilsø Christensen, Rikke Nielsen and Henrik Birn

IV. Pathophysiology of renal disease. Physiologic principles in the clinical evaluation of electrolyte, water, and acid-base disorders / Daniel Batlle, Sheldon Chen and Syed K. Haque

Biomarkers for assessment of renal function during acute kidney injury / Prasad Devarajan

Pathophysiology of acute kidney injury / Bruce A. Molitoris and Asif Sharfuddin

Ischemic renal disease / Christopher J. Cooper, Lance D. Dworkin and William L. Henrich

Pathophysiology and pathogenesis of diabetic neophropathy / sheldon Chen, Charbel Khoury and Ruad N. Ziyadeh

Renal failure in cirrhosis / Peter Ginés, Andrés Cárdenas and Robert W. Schrier

Autosomal docimant polycystic kidney disease / Stefan Somlo, Vincente E. Torres and Michael J. Caplan

Renal physiology and disease in pregnancy / Marshall D. Lindheimer, Kirk P. Conrad and S. Ananth Karumanchi

Immune and inflammatory glomerular diseases / Anup Manoharon ... [et al.]

Immunologic mechanisms of vasculitis / Jonathon W. Homeister, J. Charles Jennette and Ronald J. Falk

Genetic abnormalities in glomerular function / Yoav Segal and Clifford E. Kashtan

Celllar mechanisms of drug nephrotoxicity / Robert James Walker and Zoltán Huba Endre

Role of glomerular mechanical stress in the pathogenesis of chronic kidney disease / Clarice Kazue Fujihara and Roberto Zatz

Role of proteinuria in the progression of renal disease / Mauro Abbate ... [et al.]

The inflammatory response to ischemic acute renal injury / Christopher Y. Lu

Catalytic (labile) iron in kidney disease / Mohan Rajapurkar, Radhakrishna Baliga and Sudhir V. Shah

Chronic kidney disease: pathophysiology and the influence of dietary protein / Biruh T. Workeneh and William E. Mitch

Management of calcium and bone disease in renal patients / L. Darryl Quarles

Hematopoiesis and the kidney / Armin Kurtz, Roland H. Wenger and Kai-Uwe Eckardt

Individualizing the dialysate to address electrolyte disturbances in the dialysis patinet / Biff F. Palmer

Homeostasis of solute and water by the transplanted kidney / J. Harold Helderman ... [et al.]

Renal disposition of drugs and translation to dosing strategies / Pär Matsson, Kathleen M. Giacomini and D. Craig Brater.

Notes:

Includes bibliographical references and index.

Description based on online resource; title from electronic title page (ebrary, viewed on June 3, 2015).

Other Format:

Print version: Seldin and Giebisch's The kidney.

OCLC:

821044285

Access Restriction:

Restricted for use by site license.