Rugged free energy landscapes : common computational approaches in spin glasses, structural glasses, and biological macromolecules / edited by W. Janke.

Format:

Book

Contributor:

Janke, W. (Wolfhard), editor.

Series:

Lecture Notes in Physics, 0075-8450 ; 736

Language:

English

Subjects (All):

Spin glasses--Mathematical models.

Spin glasses.

Condensed matter--Mathematical models.

Condensed matter.

Protein folding--Mathematical models.

Protein folding.

Physical Description:

1 online resource (X, 412 p.)

Edition:

1st ed. 2008.

Place of Publication:

Berlin, Germany ; New York, New York : Springer, [2008]

Language Note:

English

Summary:

This collection of lectures and tutorial reviews by renowned experts focusses on the common computational approaches in use to unravel the static and dynamical behaviour of complex physical systems at the interface of physics, chemistry and biology. Paradigmatic examples of condensed matter physics are spin and structural glasses and protein folding, as well as their aggregation and adsorption to hard and soft surfaces, in physico-chemical biology. Among the most prominent joint key features of the systems considered in this volume are rugged free-energy landscapes. These generate metastability and are often responsible for very slow dynamics allowing for the system to be trapped in one of the many available local minima. The challenge set forth by the authors of this volume is to provide a common basis and technical language for the (computational) technology transfer between the fields and systems considered.

Contents:

Rugged Free-Energy Landscapes – An Introduction

Rugged Free-Energy Landscapes – An Introduction

Spin Glasses

Some Aspects of Infinite-Range Models of Spin Glasses: Theory and Numerical Simulations

The Potts Glass Model: A Scenario for the Freezing Transition of Structural Glasses?

Domain Walls, Droplets and Barriers in Two-Dimensional Ising Spin Glasses

Local Scale-Invariance in Disordered Systems

Structural Glasses

Transport of Mobile Particles in an Immobile Environment: Computer Simulations of Sodium Silicates

The Gonihedric Ising Model and Glassiness

Protein Folding

Thermodynamics of Protein Folding from Coarse-Grained Models’ Perspectives

Exact Energy Landscapes of Proteins Using a Coarse-Grained Model

Protein Folding, Unfolding and Aggregation Studied Using an All-Atom Model with~a~Simplified Interaction Potential

All-Atom Simulations of Proteins

Algorithmic Developments

Markov Chain Monte Carlo Methods for Simulations of Biomolecules

A Different Approach to Monte Carlo Simulations in Systems with Complex Free-Energy Landscapes

Generalized-Ensemble Algorithms for Protein Folding Simulations.

Notes:

Bibliographic Level Mode of Issuance: Monograph

Includes bibliographical references and index.

Description based on print version record.

ISBN:

9783540740292

3540740295