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Cytokine Bioassays : Methods and Protocols / edited by Ivana Vancurova.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Vancurova, Ivana, editor.
SpringerLink (Online service)
Series:
Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 1172.
Springer Protocols (Springer-12345)
Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 1172
Language:
English
Subjects (All):
Medicine.
Immunology.
Cytokines.
Growth factors.
Biomedicine.
Cytokines and Growth Factors.
Local Subjects:
Biomedicine.
Immunology.
Cytokines and Growth Factors.
Physical Description:
1 online resource (XIV, 367 pages) : 87 illustrations, 74 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana Press, 2014.
System Details:
text file PDF
Summary:
Cytokine Bioassays: Methods and Protocols provides a comprehensive collection of classic and cutting-edge methodologies that are used to analyze and quantify cytokines and their biological activities in complex biological and clinical samples. Chapters are divided into three main categories, the first category details the immunodetection of released cytokines in tissue culture supernatants, plasma, serum, and whole blood samples by immunoassays. The second part focuses on the analysis of biologically active cytokines by bioassays using neutralizing antibodies, chemotaxis assay, cytokine-induced phagocytosis assay, proteasome activity assay, and analysis of cytokine-induced immunoglobulin class switching. Part three presents analysis of intracellular cytokines by flow cytometry, immunohistochemistry, immunofluorescence confocal microscopy, and western blotting. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Cytokine Bioassays: Methods and Protocols is written by experienced, basic, and clinical researchers with hands-on knowledge of the described protocols. This book will be of interest not only to biochemists, molecular biologists and immunologists but also to physician-scientists working in the field of cytokine research.
Contents:
The Challenge of Measuring Elusive Immune Markers by Enzyme Linked Immuno-Spot (ELISPOT) Technique
Analysis of the Released Nuclear Cytokine HMGB1 in Human Serum
αELISA Based Assay for IP-10 Detection from Filter Paper Samples
Enhanced ELISA Based on Carboxymethylated Dextran Coatings
A Novel Three-Dimensional Biosensor Based on Aluminum Oxide: Application for Early Stage Detection of Human Interleukin-10
Quantification of Multiple Cytokines and Chemokines Using Cytometric Bead Arrays
A Useful Guide for Analysis of Immune Markers by Fluorochrome (Luminex) Technique
Control of Pro-inflammatory Cytokine Release from Human Monocytes with the Use of an Interleukin-10 Monoclonal Antibody
Cytokine-Induced Neutrophil Chemotaxis Assay
An In Vitro One-Dimensional Assay to Study Growth Factor-Regulated Tumor Cell-Macrophage Interaction
Chemotactic Responses by Macrophages to a Directional Source of a Cytokine Delivered by a Micropipette
Assessment of Phagocytic Activity of Cultured Macrophages Using Fluorescence Microscopy and Flow Cytometry
Assessment of Cytokine-Modulated Proteasome Activity
Evaluation of the Adverse Effect of Low Concentration of Cadmium on Interleukin-4 Induced Class Switch Recombination in Burkett's Lymphoma Raji Cell Line
A Mix-and-Measure Assay for Determining the Activation Status of Endogenous Cdc42 in Cytokine-Stimulated Macrophage Cell Lysates
Analysis of the Cell Surface Expression of Cytokine Receptors Using the Surface Protein Biotinylation Method
Detection of CXCR2 Cytokine Receptor Surface Expression Using Immunofluorescence
Detecting Tie2, an Endothelial Growth Factor Receptor, by Using Immunohistochemistry in Mouse Lungs
Use of shRNA to Stably Suppress Chemokine Receptor Expression and Function in Human Cancer Cell Lines
Intracellular Staining and Detection of Cytokines by Fluorescence-Activated Flow Cytometry
Cytokine Detection by Flow Cytometry
Analysis of IL-17 Production by Flow Cytometry and ELISPOT Assays
Interleukin-1 (IL-1) Immunohistochemistry Assay in Oral Squamous Cell Carcinoma
Immunofluorescence Confocal Microscopy of Intracellular TNF in Human Neutrophils
Evaluating Cytoplasmic and Nuclear Levels of Inflammatory Cytokines in Cancer Cells by Western Blotting
Western Analysis of Intracellular Interleukin-8 in Human Mononuclear Leukocytes
Quantitative Analysis of Bortezomib Induced IL-8 Gene Expression in Ovarian Cancer Cells
Analysis of TGFb1 and IL-10 Transcriptional Regulation in CTCL Cells by Chromatin Immunoprecipitation
Radiolabeled Semi-Quantitative RT-PCR Assay for the Analysis of Alternative Splicing of Interleukin Genes.
Other Format:
Printed edition:
ISBN:
9781493909285
Access Restriction:
Restricted for use by site license.

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