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Metabolic Profiling : Methods and Protocols / edited by Thomas O. Metz.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Metz, Thomas O., editor.
SpringerLink (Online service)
Series:
Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 708.
Springer Protocols (Springer-12345)
Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 708
Language:
English
Subjects (All):
Life sciences.
Biochemistry.
Metabolism.
Life Sciences.
Biochemistry, general.
Metabolomics.
Local Subjects:
Life Sciences.
Biochemistry, general.
Metabolomics.
Physical Description:
1 online resource (XI, 391 pages).
Contained In:
Springer eBooks
Place of Publication:
Totowa, NJ : Humana Press, 2011.
System Details:
text file PDF
Summary:
At the intersection of metabolite analysis, metabolic fingerprinting, and metabolomics, the study of metabolic profiling has evolved steadily over the course of time as have the methods and technologies involved in its study. In Metabolic Profiling: Methods and Protocols, expert researchers in the field present protocols that are illustrative of the evolution of metabolic profiling from single molecule analysis to global metabolome profiling. Comprised of the most essential techniques, this volume covers topics from inborn errors of metabolism and drug metabolite analysis to nuclear magnetic resonance metabolic profiles. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective subjects, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Metabolic Profiling: Methods and Protocols serves as a resource for both established and new investigators in this vital and ever-developing field.
Contents:
Origins of Metabolic Profiling
Amino Acid Profiling for the Diagnosis of Inborn Errors of Metabolism
Acylcarnitines: Analysis in Plasma and Whole Blood Using Tandem Mass Spectrometry
Analysis of Organic Acids and Acylglycines for the Diagnosis of Related Inborn Errors of Metabolism by GC- and HPLC-MS
HPLC Analysis of Purines and Pyrimidines for the Clinical Biochemical Diagnosis of Related Inborn Errors of Metabolism
Bile Acid Analysis in Various Biological Samples Using Ultra Performance Liquid Chromatography/Electrospray Ionization-Mass Spectrometry (LC/ESI-MS)
Analysis of Glycolytic Intermediates with Ion Chromatography- and Gas Chromatography-Mass Spectrometry
Analysis of the Citric Acid Cycle Intermediates Using Gas Chromatography-Mass Spectrometry
Quantification of Pentose Phosphate Pathway (PPP) Metabolites by Liquid Chromatography-Mass Spectrometry (LC-MS)
High Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS)-Based Drug Metabolite Profiling
Gas Chromatography-Mass Spectrometry (GC-MS)-Based Metabolomics
The Use of Two Dimensional Gas Chromatography-Time-of-Flight-Mass Spectrometry (GCxGC-TOF-MS) for Metabolomic Analysis of Polar Metabolites
LC-MS-Based Metabolomics
Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS)-Based Metabolomics
Liquid Chromatography-Mass Spectrometry (LC-MS)-Based Lipidomics for Studies of Body Fluids and Tissues
Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS)-Based Shotgun Lipidomics
Processing and Analysis of GC/LC-MS-Based Metabolomics Data
Nuclear Magnetic Resonance (NMR)-Based Drug Metabolite Profiling
Nuclear Magnetic Resonance (NMR)-Based Metabolomics
Slow Magic Angle Sample Spinning: A Non- or Minimal-Invasive Method for High Resolution 1H Nuclear Magnetic Resonance (NMR) Metabolic Profiling
Processing and Modeling of Nuclear Magnetic Resonance (NMR) Metabolic Profiles.
Other Format:
Printed edition:
ISBN:
9781617379857
Access Restriction:
Restricted for use by site license.

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