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Molecular Beacons: Signalling Nucleic Acid Probes, Methods, and Protocols / edited by Andreas Marx, Oliver Seitz.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Marx, Andreas, editor.
Seitz, Oliver, Dr., editor.
SpringerLink (Online service)
Series:
Methods in molecular biology 1064-3745 ; 429.
Springer Protocols (Springer-12345)
Methods in Molecular Biology, 1064-3745 ; 429
Language:
English
Subjects (All):
Medicine.
Human genetics.
Biotechnology.
Internal medicine.
Animal genetics.
Medicine & Public Health.
Internal Medicine.
Human Genetics.
Animal Genetics and Genomics.
Local Subjects:
Medicine & Public Health.
Internal Medicine.
Human Genetics.
Biotechnology.
Animal Genetics and Genomics.
Physical Description:
1 online resource (XII, 266 pages) : 77 illustrations, 17 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
Totowa, NJ : Humana Press, 2008.
System Details:
text file PDF
Summary:
Significant DNA sequence data has been made available by several important genome projects. The allocation of functions to a mere string of the four letters in the code of life plays a major if not predominant role of ongoing and future research. Guided by experts in the field, Molecular Beacons: Signalling Nucleic Acid Probes, Methods, and Protocols, provides easy-to-follow experiments, commences with an introduction to the basic principles of fluorescence, and shows a diverse set of instructive examples, from probe design to applications in clinical settings, molecular beacon technology, the identification of transgenic mice, along with the potential of realtime PCR. While originally being used for fluorogenic nucleic acid probes with a stem-loop structure, molecular beacon now refers to a whole family of fluorescence-up probes. Molecular Beacons: Signalling Nucleic Acid Probes, Methods, and Protocols summarizes all the latest findings and explores powerful techniques designed for geneticist, biotechnologists, molecular and cellular biologists, researchers and developers.
Contents:
Basic Principles of Fluorescence and Energy Transfer
Applications
Multiplex Detection of Mutations
Detection of Salmonella Species in Foodstuffs
Identification of Homozygous Transgenic Mice by Genomic Real-Time PCR
Quantitative Analysis of Gene Expression Relative to 18S rRNA in Carcinoma Samples Using the LightCycler® Instrument and a SYBR GreenI-based Assay: Determining FAT10 mRNA Levels in Hepatocellular Carcinoma
Absolute Quantitation of Feline Leukemia Virus Proviral DNA and Viral RNA Loads by TaqMan® Real-time PCR and RT-PCR
High-Throughput Real-Time PCR
Design and Use of Scorpions Fluorescent Signaling Molecules
Hybridization Probe Pairs and Single-Labeled Probes: an Alternative Approach for Genotyping and Quantification
New Technologies
EasyBeacons™ for the Detection of Methylation Status of Single CpG Duplets
Quenched Autoligation Probes
HyBeacon® Probes for Rapid DNA Sequence Detection and Allele Discrimination
FIT-Probes in Real-Time PCR
SNP Genotyping by Unlabeled Probe Melting Analysis
Non-Nucleic Acid Targets
Molecular Beacons for Protein-DNA Interaction Studies
DNA Polymerase Profiling
Modular Reporter Hairpin Ribozymes for Analyzing Molecular Interactions
Screening of Molecular Interactions Using Reporter Hammerhead Ribozymes.
Other Format:
Printed edition:
ISBN:
9781603270403
Access Restriction:
Restricted for use by site license.

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