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Hematopoietic Stem Cell Protocols / edited by Kevin D. Bunting.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Bunting, Kevin D., editor.
SpringerLink (Online service)
Series:
Methods in molecular biology 1064-3745 ; 430.
Springer Protocols (Springer-12345)
Methods in Molecular Biology™, 1064-3745 ; 430
Language:
English
Subjects (All):
Life sciences.
Molecular biology.
Hematology.
Biochemistry.
Cytology.
Life Sciences.
Biochemistry, general.
Cell Biology.
Molecular Medicine.
Local Subjects:
Life Sciences.
Biochemistry, general.
Cell Biology.
Hematology.
Molecular Medicine.
Physical Description:
1 online resource (XIV, 312 pages).
Edition:
Second Edition.
Contained In:
Springer eBooks
Place of Publication:
Totowa, NJ : Humana Press, 2008.
System Details:
text file PDF
Summary:
With new technologies emerging and old technologies being reimagined, the field of hematopoietic stem cell (HSC) research continues to grow rapidly in pursuit of improved therapies for many blood diseases. Updating and building upon the thorough first edition's foundation, Hematopoietic Stem Cell Protocols, Second Edition provides up-to-date protocols developed in the HSC field. A team of leading researchers supply this volume with in-depth, readily reproducible methods for effective characterization of HSC and their developmental potential. An introductory chapter also hints at potential techniques that may develop in the future. Following the format of the successful Methods in Molecular Biology™ series, each protocol offers step-by-step laboratory instructions, lists of the necessary equipment, and tips on troubleshooting and avoiding known pitfalls. Essential for the laboratory-based researcher, Hematopoietic Stem Cell Protocols, Second Edition is a much needed technical resource in the critically important field of stem cell investigation.
Contents:
Overview
The Expanding Tool Kit for Hematopoietic Stem Cell Research
Stem Cell Enrichment and Analysis
Isolation of Quiescent Murine Hematopoietic Stem Cells by Homing Properties
Mobilization of Hematopoietic Stem and Progenitor Cells in Mice
Transmigration of Human CD34+ Cells
Flow Cytometry-Based Cell Cycle Measurement of Mouse Hematopoietic Stem and Progenitor Cells
Analysis of Apoptosis in Hematopoietic Stem Cells by Flow Cytometry
In Vitro Assays and Differentiation
In Vitro Hematopoietic Differentiation of Murine Embryonic Stem Cells
Hematopoietic Development of Human Embryonic Stem Cells in Culture
In Vitro Human T Cell Development Directed by Notch-Ligand Interactions
In Vitro Assays for Cobblestone Area-Forming Cells, LTC-IC, and CFU-C
Transplantation Assays for Mouse and Human HSC
Hematopoietic Stem Cell Transplant in Mice by Intra-Femoral Injection
Hematopoietic Stem Cell Transplant into Non-Myeloablated W/W v Mice to Detect Steady-State Engraftment Defects
Isolation and Functional Characterization of Side Population Stem Cells
Transplantation of Chimeric Fetal Liver to Study Hematopoiesis
Immunodeficient Mouse Models to Study Human Stem Cell-Mediated Tissue Repair
Genetic Modification of HSCs and Imaging Engraftment
Retroviral Transduction of Murine Hematopoietic Stem Cells
Lentiviral Gene Transduction of Mouse and Human Stem Cells
Retroviral Integration Site Analysis in Hematopoietic Stem Cells
A Detailed Protocol for Bacterial Artificial Chromosome Recombineering to Study Essential Genes in Stem Cells
Bioluminescence Imaging of Hematopoietic Stem Cell Repopulation in Murine Models.
Other Format:
Printed edition:
ISBN:
9781597451826
Access Restriction:
Restricted for use by site license.

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