2 options
Telomerase Inhibition : Strategies and Protocols / edited by Lucy G. Andrews, Trygve O. Tollefsbol.
Connect to full text Available online
View onlineHolman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
Available
- Format:
- Book
- Series:
- Methods in molecular biology 1064-3745 ; 405.
- Springer Protocols (Springer-12345)
- Methods in Molecular Biology™, 1064-3745 ; 405
- Language:
- English
- Subjects (All):
- Life sciences.
- Cancer--Research.
- Cancer.
- Human genetics.
- Biochemistry.
- Cytology.
- Life Sciences.
- Cell Biology.
- Cancer Research.
- Human Genetics.
- Biochemistry, general.
- Local Subjects:
- Life Sciences.
- Cell Biology.
- Cancer Research.
- Human Genetics.
- Biochemistry, general.
- Physical Description:
- 1 online resource (X, 193 pages).
- Contained In:
- Springer eBooks
- Place of Publication:
- Totowa, NJ : Humana Press, 2007.
- System Details:
- text file PDF
- Summary:
- Due in part to the selective nature of telomerase inhibition as an anticancer approach, the field has expanded considerably in the past decade. The recent advances in methods of telomerase inhibition encompass many different areas of research including molecular biology, cell biology, biochemistry, oncology and gerontology. Telomerase Inhibition provides methods and protocols for those researchers. The techniques described in this book should provide the researcher with a diverse and comprehensive set of tools with which to study telomerase inhibition. Leaders in the field provide recently developed methods that have widespread application such as targeting the telomerase holoenzyme, its RNA template and other elements associated with telomerase activity. Additional methods involving the screening of telomerase inhibitors and telomerase inhibition combined with other chemotherapeutic agents are presented. This text, on the cutting edge of the field, will provide investigators with the most recent methods applied to the expanding field of telomerase inhibition.
- Contents:
- Methods of Telomerase Inhibition
- Telomerase Inhibition by Synthetic Nucleic Acids and Chemosensitization in Human Bladder Cancer Cell Lines
- hTERT Knockdown in Human Embryonic Kidney Cells Using Double-Stranded RNA
- RNA Interference Using a Plasmid Construct Expressing Short-Hairpin RNA
- Retrovirus-Mediated RNA Interference
- Telomerase Inhibition and Telomere Targeting in Hematopoietic Cancer Cell Lines with Small Non-Nucleosidic Synthetic Compounds (BIBR1532)
- Uses of Telomerase Peptides in Anti-Tumor Immune Therapy
- Establishing Cell-Based Reporter Systems for the Analysis of hTERT Expression
- Telomerase RNA Inhibition Using Antisense Oligonucleotide Against Human Telomerase RNA Linked to a 2?,5?-Oligoadenylate
- Knockdown of Telomerase RNA Using Hammerhead Ribozymes and RNA Interference
- Evaluation of Tankyrase Inhibition in Whole Cells
- Inhibition of Telomerase by Targeting MAP Kinase Signaling
- Screening of Telomerase Inhibitors
- Telomerase Inhibition Combined with Other Chemotherapeutic Reagents to Enhance Anti-Cancer Effect.
- Other Format:
- Printed edition:
- ISBN:
- 9781603270700
- Access Restriction:
- Restricted for use by site license.
The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.