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PRINS and In Situ PCR Protocols / edited by John R. Gosden.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Gosden, John R., editor.
SpringerLink (Online service)
Series:
Methods in molecular biology 1064-3745 ; 71.
Springer Protocols (Springer-12345)
Methods in Molecular Biology™, 1064-3745 ; 71
Language:
English
Subjects (All):
Life sciences.
Cytology.
Life Sciences.
Cell Biology.
Local Subjects:
Life Sciences.
Cell Biology.
Physical Description:
1 online resource (XIII, 165 pages) : 75 illustrations, 22 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
Totowa, NJ : Humana Press, 1997.
System Details:
text file PDF
Summary:
Cutting edge researchers demonstrate step-by-step how oligonucleotide primers may be successfully used to detect and amplify or extend complimentary sequences in situ. Through these procedures-often invented by the authors-the door is opened to rapid identification and characterization of chromosomal DNA sequences, viral genomes, and rare messenger RNAs in cells-at hitherto unmatched degrees of sensitivity and specificity. Their innovative techniques-suitable for both novice and experienced researchers-have rapidly become indispensable for many clinical diagnostic procedures, whether in quantification of chromosomes in the identification of aneuploidy for prenatal diagnosis, or in the identification of viral infection in the early stages, or of rare messenger RNAs present in cells.
Contents:
Oligonucleotide PRINS DNA Synthesis
Chromosome-Specific PRINS
Bright-Field Microscopic Detection of Oligonucleotide PRINS-Labeled DNA in Chromosome Preparations
Analysis of Sperm Aneuploidy by PRINS
PRINS DNA Synthesis on Frozen Tissue Sections
Multiple Sequential Oligonucleotide Primed In Situ DNA Syntheses (MULTI-PRINS)
Oligonucleotide PRINS DNA Synthesis on Extended Chromatin Preparations
Combined lmmunocytochemistry and PRINS DNA Synthesis for Simultaneous Detection of Phenotypic and Genomic Parameters in Cells
Chromosomal PRINS DNA Labeling Combined with Indirect Immunocytochemistry
Direct In Situ Single-Copy (DISC)-PCR
In Situ PCR to Cells and to Wax Sections
Reverse Transcriptase PCR In Situ on Cryopreserved Tissue Sections
Flow Cytometry Analysis of an In Situ PCR for the Detection of Human Immunodeficiency Virus Type-1 (HIV-1) Proviral DNA
In Situ PCR Amplification of Intracellular mRNA
Localized In Situ Amplification (LISA)
In Situ PCR.
Other Format:
Printed edition:
ISBN:
9781592595570
Access Restriction:
Restricted for use by site license.

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