Lung Cancer : Volume 2: Diagnostic and Therapeutic Methods and Reviews / edited by Barbara Driscoll.

Format:

Book

Contributor:

Driscoll, Barbara, editor.

SpringerLink (Online service)

Series:

Methods in molecular medicine 1543-1894 ; 75.

Springer Protocols (Springer-12345)

Methods in Molecular Medicine™, 1543-1894 ; 75

Language:

English

Subjects (All):

Medicine.

Oncology.

Medicine & Public Health.

Local Subjects:

Medicine & Public Health.

Oncology.

Physical Description:

1 online resource (XXIII, 816 pages).

Contained In:

Springer eBooks

Place of Publication:

Totowa, NJ : Humana Press : Imprint: Humana Press, 2003.

System Details:

text file PDF

Summary:

Molecular-based laboratory methods can help significantly in the diagnosis and treatment of lung cancer, a leading cause of death worldwide. In Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews, leading physicians, scientists, and noted researchers describe step-by-step techniques for lung cancer diagnosis based on the molecular analysis of clinical samples. These experts review currently accepted treatments and outline a variety of novel therapies, including treatments based on gene therapy, immunotherapy, and chemoprevention, and show how these newly improved techniques can give a better appreciation of the prognosis associated with the particular mutation uncovered by the technique. These methods use a variety of molecular techniques, including the manipulation of gene expression and the alteration of immune status, to combat lung cancer. A companion volume, Lung Cancer, Volume 1: Molecular Pathology Methods and Reviews, illuminates the etiology of lung cancer and provides reliable techniques for detecting the responsible genetic mutations at the cellular, DNA, and protein levels. Comprehensive and informative, Lung Cancer, Volume 2: Diagnostic and Therapeutic Methods and Reviews illuminates how molecular approaches can and are being applied to the diagnosis of lung cancer. Together, these two volumes constitute an unprecedented resource for those who wish to better understand how this disease is being diagnosed and treated, and what novel techniques may be available to improve both processes.

Contents:

Molecular and Genetic Aspects of Lung Cancer

Detection of Altered Tumor Markers in Clinical Samples for Diagnosis and Prognosis

Molecular Alterations in Lung Cancer

Cellular Predictive Factors of Drug Resistance in Non-Small Cell Lung Carcinomas

Clinical Implications of p53 Mutations in Lung Cancer

An Epidemiologic and Clinicopathologic Overview of AIDS-Associated Pulmonary Kaposi's Sarcoma

Myeloperoxidase Promoter Region Polymorphism and Lung Cancer Risk

Clinical Utility of Tumor Markers in the Management of Non-Small Cell Lung Cancer

Detection of Chromosomal Aberrations in Lung Tissue and Peripheral Blood Lymphocytes Using Interphase Fluorescence In Situ Hybridization (FISH)

In Situ Analysis of Telomerase RNA Gene Expression as a Marker for Tumor Progression

A High-Throughput Methodology for Identifying Molecular Targets Overexpressed in Lung Cancers

Expression Profiling of Lung Cancer Based on Suppression Subtraction Hybridization (SSH)

Comparative Genomic Hybridization of Human Lung Cancer

Sensitive Assays for Detection of Lung Cancer

Fluorescent Microsatellite Analysis in Bronchial Lavage as a Potential Diagnostic Tool for Lung Cancer

Southern Blotting of Genomic DNA from Lung and Its Tumors

Assessment of Insulin-Like Growth Factors and Mutagen Sensitivity as Predictors of Lung Cancer Risk

Comparative Multiplex PCR and Allele-Specific Expression Analysis in Human Lung Cancer

Detection of K-ras Point Mutations in Sputum from Patients with Adenocarcinoma of the Lung by Point-EXACCT

Detection of K-ras and p53 Mutations by "Mutant-Enriched" PCR-RFLP

Detection of Small Cell Lung Cancer by RT-PCR for Neuropeptides, Neuropeptide Receptors, or a Splice Variant of the Neuron Restrictive Silencer Factor

Utilization of Thyroid Transcription Factor-1 Immunostaining in the Diagnosis of Lung Tumors

Molecular Biologic Substaging of Stage I NSCLC Through Immunohistochemistry Performed on Formalin-Fixed, Paraffin-Embedded Tissue

A Sensitive Immunofluorescence Assay for Detection of p53 Protein in the Sputum

SPR1

Determination of Biological Parameters on Fine-Needle Aspirates from Non-Small Cell Lung Cancer

Detection and Analysis of Lung Cancer Cells from Body Fluids Using a Rare Event Imaging System

Reconstruction of Geno-Phenotypic Evolutionary Sequences from Intracellular Patterns of Molecular Abnormalities in Human Solid Tumors

Novel Therapies

Surgical Treatment of Lung Cancer

Recent Advances and Dilemmas in the Radiotherapeutic Management of Locally Advanced Non-Small Cell Lung Cancer

Photodynamic Therapy in Lung Cancer

Gene Therapy for Lung Cancer

Identifying Obstacles to Viral Gene Therapy for Lung Cancer

Topical Gene Therapy for Pulmonary Diseases with PEI-DNA Aerosol Complexes

Targeted Delivery of Expression Plasmids to the Lung via Macroaggregated Polyethylenimine-Albumin Conjugates

Preparation of Retroviral Vectors for Cell-Cycle-Targeted Gene Therapy of Lung Cancer

Aerosol Gene Therapy for Metastatic Lung Cancer Using PEI-p53 Complexes

Clinical Development of Antisense Oligonucleotides as Anti-Cancer Therapeutics

Antisense Oligonucleotides Targeting RI? Subunit of Protein Kinase A

Use of Antisense Oligonucleotides for Therapy

Induction of Programmed Cell Death with an Antisense Bcl-2 Oligonucleotide

Tumor Vaccination with Cytokine-Encapsulated Microspheres

Adoptive Immunotherapy

Intratumoral Therapy with Cytokine Gene-Modified Dendritic Cells in Murine Lung Cancer Models

Cyclooxygenase 2-Dependent Regulation of Antitumor Immunity in Lung Cancer

Chemoprevention of Lung Cancer

Assessing the Interaction of Particulate Delivery Systems with Lung Surfactant

Chemopreventive Therapeutics.

Other Format:

Printed edition:

ISBN:

9781592593248

Access Restriction:

Restricted for use by site license.