Advanced Patch-Clamp Analysis for Neuroscientists / edited by Alon Korngreen.

Format:

Book

Contributor:

Korngreen, Alon, editor.

SpringerLink (Online service)

Series:

Neuromethods 0893-2336 ; 113.

Springer Protocols (Springer-12345)

Neuromethods, 0893-2336 ; 113

Language:

English

Subjects (All):

Neurosciences.

Local Subjects:

Neurosciences.

Physical Description:

1 online resource (XII, 350 pages) : 81 illustrations, 28 illustrations in color.

Contained In:

Springer eBooks

Place of Publication:

New York, NY : Springer New York : Imprint: Humana Press, 2016.

System Details:

text file PDF

Summary:

This volume presents current adaptations of the patch-clamp technique to neuroscience. Chapters focus on in-vivo recordings, voltage-gated channel recording and analysis, dendritic and axonal recordings, synaptic current recording and analysis, advanced fluorescent techniques, optogenetics and voltage-sensitive dye imaging, and finally channel and neuronal modeling. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Advanced Patch-Clamp Analysis for Neuroscientists aims to ensure successful results in the further study of this vital field.

Contents:

In Vivo Whole-Cell Recordings

Juxtasomal Loose-Patch Recordings in Awake, Head-Fixed Rats to Study the Link between Structure and Function of Individual Neurons

Studying Sodium Channel Gating In Heterologous Expression Systems

Elucidating the Link between Structure and Function of Ion Channels and Transporters with Voltage-Clamp and Patch-Clamp Fluorometry

Dendrites: Recording from Fine Neuronal Structures Using Patch-Clamp and Imaging Techniques

Patch-clamp Recording from Myelinated Central Axons

Analysis of Transsynaptic Attentional Neuronal Circuits with Octuple Patch-Clamp Recordings

Optogenetic Dissection of the Striatal Microcircuitry

Paired Recordings from Synaptically Coupled Neurones in Acute Neocortical Slices

Extracting Quantal Properties of Transmission at Central Synapses

Acousto-optical Scanning-Based High Speed 3D Two-Photon Imaging In Vivo

Intracellular Voltage-Sensitive Dyes for Studying Dendritic Excitability and Synaptic Integration

Modeling the Kinetic Mechanisms of Voltage-Gated Ion Channels

Recording and Hodgkin-Huxley Kinetic Analysis of Voltage-Gated Ion Channels in Nucleated Patches

Creating and Constraining Compartmental Models of Neurons Using Experimental Data.

Other Format:

Printed edition:

ISBN:

9781493934119

Access Restriction:

Restricted for use by site license.