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Genetic Epidemiology / edited by M. Dawn Teare.
Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
Available
- Format:
- Book
- Series:
- Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 713.
- Springer Protocols (Springer-12345)
- Methods in Molecular Biology, Methods and Protocols, 1064-3745 ; 713
- Language:
- English
- Subjects (All):
- Medicine.
- Human genetics.
- Medical genetics.
- Biomedicine.
- Human Genetics.
- Gene Function.
- Local Subjects:
- Biomedicine.
- Human Genetics.
- Gene Function.
- Physical Description:
- 1 online resource (XII, 242 pages).
- Contained In:
- Springer eBooks
- Place of Publication:
- Totowa, NJ : Humana Press : Imprint: Humana Press, 2011.
- System Details:
- text file PDF
- Summary:
- Arising from firm foundations laid by mathematical population genetics, clinical genetics, and statistical epidemiology, genetic epidemiology attempts to identify the many components of risk attributable to genes, environments, and interactions, and the course of its research can follow many diverse paths. In Genetic Epidemiology, the success of genome-wide association studies in their identification of hundreds of disease susceptibility loci has inspired renowned experts to contribute thorough methodologies, which aim to bring together bioinformaticians, geneticists, clinicians, statisticians, and epidemiologists in the study of this vital field. The volume opens with chapters covering the basics; however, it quickly moves on to coverage of more specialist topics such as twin studies, Mendelian randomization, genetic association studies, more advanced areas, as well as case studies. As a part of the highly successful Methods in Molecular Biology™ series, this work provides the detailed description of the application and analysis of the most commonly employed methods that are necessary for a firm grounding in the field. Authoritative and cutting-edge, Genetic Epidemiology aims to provide a basic framework for crucial interdisciplinary communication and understanding suited to newcomers to the field as well as experienced researchers and graduate level students.
- Contents:
- Molecular Genetics and Genetic Variation
- Terminology, Concepts, and Models in Genetic Epidemiology
- An Introduction to Epidemiology
- Genetic Distance and Markers Used in Linkage Mapping
- Approaches to Genetic Linkage Analysis
- Fine-Scale Structure of the Genome and Markers Used in Association Mapping
- Genome-Wide Association Studies
- Candidate Gene Association Studies
- Family-Based Association Studies
- Genome Variation: A Review of Web Resources
- Advanced Methods in Twin Studies
- Mendelian Randomization: A Tool for Assessing Causality in Observational Epidemiology
- Copy Number Variation
- Epigenetic Variation
- Modeling the Effect of Susceptibility Factors (HLA and PTPN22) in Rheumatoid Arthritis
- Coronary Artery Disease: An Example Case Study
- The Genetic Epidemiology of Obesity: A Case Study.
- Other Format:
- Printed edition:
- ISBN:
- 9781603274166
- Access Restriction:
- Restricted for use by site license.
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