Biology of Chlamydia / edited by Georg Häcker.

Format:

Book

Contributor:

Häcker, Georg, editor.

SpringerLink (Online service)

Series:

Current topics in microbiology and immunology 0070-217X ; 412.

Current Topics in Microbiology and Immunology, 0070-217X ; 412

Language:

English

Subjects (All):

Microbiology.

Immunology.

Emerging infectious diseases.

Medical Microbiology.

Infectious Diseases.

Local Subjects:

Medical Microbiology.

Immunology.

Infectious Diseases.

Physical Description:

1 online resource (X, 237 pages).

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2018.

System Details:

text file PDF

Summary:

The genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria - which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell's defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.

Contents:

Cell wall biosynthesis in Chlamydia

Genetic manipulation in Chlamydia

Early events in the Chlamydia developmental cycle

Subversion of the host cell cytoskeleton by Chlamydia

Cell-autonomous host defence against Chlamydia infection

The enigma of long-term infection: are there quiescent or 'persistent' Chlamydia?- Mechanisms of immunopathogenesis during chlamydial infections

Protective adaptive immune response and prospects for a vaccine

The hidden genomics of Chlamydia trachomatis.

Other Format:

Printed edition:

ISBN:

9783319712321

Access Restriction:

Restricted for use by site license.