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Introduction to cancer biology : a concise journey from epidemiology through cell and molecular biology to treatment and prospects / Robin Hesketh.
Holman Biotech Commons RC261 .H58 2013
Available
- Format:
- Book
- Author/Creator:
- Hesketh, Robin.
- Language:
- English
- Subjects (All):
- Cancer.
- Carcinogenesis.
- Tumors.
- Biology.
- Neoplasms.
- Neoplastic Processes.
- Oncogenes.
- Sequence Analysis, DNA.
- Medical Subjects:
- Neoplasms.
- Neoplastic Processes.
- Oncogenes.
- Sequence Analysis, DNA.
- Physical Description:
- xvii, 335 pages : illustrations
- Place of Publication:
- Cambridge : Cambridge University Press, 2013.
- Summary:
- "This concise overview of the fundamental concepts of cancer biology is ideal for those with little or no background in the field. A summary of global cancer patterns introduces students to the general principles of how cancers arise and the risk factors involved. By focusing on fundamental examples of the signalling pathways within cells, the functional effects of DNA damage are explained. Later chapters then build on this foundation to provide a comprehensive summary of the major signalling pathways that affect tumour development. Current therapeutic strategies are reviewed, along with a discussion of methods for tumour detection and biomarker identification. Finally, the impact of whole genome sequencing is discussed, bringing students up to date with key recent developments in the field. From basic principles to insights into cutting-edge research, this book will enable the reader to move into the cancer field with confidence"--Provided by publisher.
- Contents:
- Lessons from epidemiology
- Causes of cancer
- Signalling in normal cells
- 'Cancer genes' : mutations and cancer development
- What is a tumour?
- Cancer signalling networks
- The future of cancer prevention, diagnosis and treatment
- The future of cancer in the post-genomic era
- Appendix A. Tumour grading and staging
- Appendix B. Targets of specific anti-cancer drugs
- Appendix C. Classes of major oncoproteins
- Appendix D. Major tumour suppressor genes
- Appendix E. Ten major cancers at a glance
- Glossary and abbreviations.
- Notes:
- Includes bibliographical references and index.
- ISBN:
- 9781107013988
- 1107013984
- 9781107601482
- 1107601487
- OCLC:
- 828413238
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