Children in medical research : access versus protection / Lainie Friedman Ross.

Format:

Book

Author/Creator:

Ross, Lainie Friedman, author.

Series:

Issues in biomedical ethics.

Issues in biomedical ethics

Language:

English

Subjects (All):

Pediatrics--Research--Moral and ethical aspects.

Pediatrics.

Children--Research--Moral and ethical aspects.

Children.

Human experimentation in medicine--United States.

Human experimentation in medicine.

Children--Legal status, laws, etc--United States.

Human Experimentation--legislation & jurisprudence.

Human Experimentation--ethics.

Child.

Human Experimentation.

United States.

Medical Subjects:

Human Experimentation--legislation & jurisprudence.

Human Experimentation--ethics.

Child.

Human Experimentation.

United States.

Physical Description:

1 online resource (xi, 285 pages)

Other Title:

Access versus protection

Place of Publication:

Oxford : Oxford University Press, 2006.

Language Note:

English

Summary:

Lainie Ross presents a rigorous critical investigation of the development of policy governing the involvement of children in medical research. She examines the shift in focus from protection of medical research subjects, enshrined in post-World War II legislation, to the current era in which access is assuming greater precedence. Infamous studies such as Willowbrook (where mentally retarded children were infected with hepatitis) are evidence that before the policy shift protectionwas not always adequate, even for the most vulnerable groups. Additional safeguards for children were first impleme

Contents:

SECTION 1: ACCESS VERSUS PROTECTION: From 1966 to 2005: Balancing protection and access to pediatric research

Access versus protection: Minority representation in pediatric research

SECTION 2: CHALLENGES TO THE REGULATIONS: Overview of the common rule and subpart D

Should we provide healthy children with greater protection in medical research?

Informed consent in pediatric research

Phase I research and the meaning of 'Prospect of direct benefit'

SECTION 3: STRENGTHS AND LIMITS OF CURRENT REGULATIONS: Human subject protections in published pediatric research

Research in schools

SECTION 4: CASE STUDIES: Minimizing risks: Diabetes research in newborns

Diabetes prediction and prevention research in childhood

Lead abatement research

Clinical asthma trials

Research not otherwise approvable: A look at one 407 protocol

Evolution of the 407 process.

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

Description based on publisher supplied metadata and other sources.

ISBN:

0-19-923042-0

1-281-16453-4

9786611164539

0-19-153421-8

1-4237-6815-9

OCLC:

67552814