Integrin Targeting Systems for Tumor Diagnosis and Therapy / edited by Eleonora Patsenker.

Format:

Book

Contributor:

Patsenker, Eleonora, editor.

SpringerLink (Online service)

Series:

Methods in pharmacology and toxicology 1557-2153

Methods in Pharmacology and Toxicology, 1557-2153

Language:

English

Subjects (All):

Medicine.

Pharmacology.

Biomedicine.

Pharmacology/Toxicology.

Local Subjects:

Biomedicine.

Pharmacology/Toxicology.

Physical Description:

1 online resource (XI, 226 pages) : 68 illustrations.

Contained In:

Springer eBooks

Place of Publication:

New York, NY : Springer New York : Imprint: Humana Press, 2018.

System Details:

text file PDF

Summary:

This volume collects a variety of techniques and methodologies developed to facilitate research on integrin biology and to identify ideal targets and approaches for the treatment of multiple organ diseases, with a focus on cancer in particular. The chapters consecutively describe the tools for structural analysis, identification and detection of integrins as biomarkers, and include thorough laboratory and clinically-related methods on different strategies for generation, synthesis and evaluation of probes, carriers, peptides or small particles for integrin targeting, imaging, and drug delivery. As part of the Methods in Pharmacology and Toxicology series, this book contains the practical details that are invaluable in the laboratory. Authoritative and advantageous, Integrin Targeting Systems for Tumor Diagnosis and Therapy serves readers from a wide spectrum, including researchers and students seeking an overview of existing developments, as well as leading professionals aiming to become more familiar with integrin-related innovative technologies in cancer research.

Contents:

Tumor Targeting by RGD-Grafted PLGA-Based Nanotheranostics Loaded with Paclitaxel and Superparamagnetic Iron Oxides

Fabrication of cRGD Conjugated Dual Responsive Micelles to Target αvβ5 Integrin Overexpressed Cancer.- Copper-Free Click Chemistry Modification of Nanovectors for Integrin Targeted Cancer Therapy.- Preparation, Characterization, and In Vitro and In Vivo Evaluation of PEGylated Liposomal Doxorubicin Modified with Different cRGD Peptides

Preparation of Heterobivalent and Multivalent Radiopharmarmaceuticals to Target Tumors Over-Expressing Integrins.- 177Lu Labeled RGD-BBN Peptide for Targeting Prostate Cancer

Integrin-Mediated Targeting of Liposomally-Bound siRNAs to Tumor Vasculatures

Integrin αvβ3-Targeted Optical Imaging with Metal Oxide Nanomaterials: Focusing on Zinc Oxide

Integrin Targeting Using RGD-Based Peptide Amphiphiles

Cyclic-RGDfK-Directed Docetaxel Loaded Nanomicelles for Angiogenic Tumor Targeting

Targeting Glioma Cancer Cells with Fluorescent Nanodiamonds Via Integrin Receptors.- NIR Imaging-Guided Photothermal Therapy by cRGD-Conjugated Solid Lipid Nanoparticles Encapsulating IR-780

Synergistic Active Targeting to B16F10 Tumors by αvβ3/CD44-Targeted Nanoparticles Loaded with Docetaxel.

Other Format:

Printed edition:

ISBN:

9781493974450

Access Restriction:

Restricted for use by site license.