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Computational Systems Biology : Methods and Protocols / edited by Tao Huang.

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Holman Biotech Commons QH506 .M45 v.1 (1984)-v.20 (1993),v.22 (1994),v.24 (1994)-v.53 (1996), v.42 (1995) and v.51 (1995) reported missing 3-13-2000 v.55 (1995),v.58 (1996)-v.63 (1997), v.65 (1996)-v.154 (2001), v.156 (2001)-190 (2002), v.192 (2002)-v.407 (2007) v.409 (2007)-v.416 (2008),v.418 (2008)-v.466 v.468-v.490,v.492,v.494,v.496-499 501-506,508,510-512,514,516-517,519-536 538,540-569,571 573-589,591-608,610-615,617,620-627,630-633,636,638,642
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Format:
Book
Contributor:
Huang, Tao (Of the Shanghai Institutes for Biological Sciences), editor.
SpringerLink (Online service)
Series:
Methods in molecular biology 1064-3745 ; 1754.
Methods in Molecular Biology, 1064-3745 ; 1754
Language:
English
Subjects (All):
Life sciences.
Bioinformatics.
Life Sciences.
Local Subjects:
Life Sciences.
Bioinformatics.
Physical Description:
1 online resource (XII, 417 pages) : 48 illustrations, 38 illustrations in color.
Contained In:
Springer eBooks
Place of Publication:
New York, NY : Springer New York : Imprint: Humana Press, 2018.
System Details:
text file PDF
Summary:
This volume introduces the reader to the latest experimental and bioinformatics methods for DNA sequencing, RNA sequencing, cell-free tumour DNA sequencing, single cell sequencing, single-cell proteomics and metabolomics. Chapters detail advanced analysis methods, such as Genome-Wide Association Studies (GWAS), machine learning, reconstruction and analysis of gene regulatory networks and differential coexpression network analysis, and gave a practical guide for how to choose and use the right algorithm or software to handle specific high throughput data or multi-omics data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Computational Systems Biology: Methods and Protocols aims to ensure successful results in the further study of this vital field. .
Contents:
DNA Sequencing Data Analysis
Transcriptome Sequencing: RNA-seq
Capture Hybridization of Long-range DNA Fragments for High-throughput Sequencing
The Introduction and Clinical Application of Cell-free Tumour DNA
Bioinformatics Analysis for Cell-free Tumor DNA Sequencing Data
An Overview of Genome-Wide Association Studies
Integrative Analysis of Omics Big Data
The Reconstruction and Analysis of Gene Regulatory Networks
Differential Coexpression Network Analysis for Gene Expression Data
iSeq: Web-based RNA-seq Data Analysis and Visualization
Revisit of Machine Learning Supported Biological and Biomedical Studies
Identifying Interactions Between Long Non-coding RNAs and Diseases Based on Computational Methods
Survey Of Computational Approaches For Prediction of DNA-binding Residues on Protein Surfaces
Computational Prediction of Protein O-GlcNAc Modification
Machine Learning Based Modeling of Drug Toxicity
Metabolomics: A High-throughput Platform for Metabolite Profile Exploration
Single-Cell Protein Assays
A Review
Data Analysis in Single-cell Transcriptome Sequencing
Applications of Single-cell Sequencing For Multi-omics
Progress on Diagnosis of Tuberculous Meningitis
Insights of Acute Lymphoblastic Leukemia with Development of Genomic Investigation.
Other Format:
Printed edition:
ISBN:
9781493977178
Access Restriction:
Restricted for use by site license.

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