Introduction to computational proteomics / Golan Yona.

Format:

Book

Author/Creator:

Yona, Golan, author.

Series:

Chapman and Hall/CRC mathematical & computational biology series

Chapman & Hall/CRC mathematical and computational biology series

Language:

English

Subjects (All):

Proteomics--Mathematical models.

Proteomics.

Proteomics--methods.

Mathematical models.

Proteómica--Modelos matemáticos.

Medical Subjects:

Proteomics--methods.

Local Subjects:

Proteómica--Modelos matemáticos.

Physical Description:

xxii, 739 pages : illustrations (some color) ; 25 cm.

Place of Publication:

Boca Raton : CRC Press, [2011]

Summary:

"This book tackles the steps and problems involved with protein analysis, classification, and meta-organization. It starts with the analysis of individual entities and proceeds to the analysis of more complex entities, from protein families to interactions, cellular pathways, and gene networks. The first part of the book presents methods for identifying the building blocks of the protein space, algorithms for assessing similarity between proteins, and mathematical models for representing protein families and classifying new instances. The second part covers methods that investigate higher order structure in the protein space through the application of unsupervised learning algorithms"--Provided by publisher.

Contents:

I The basics: What is computational proteomics?

Basic notions in molecular biology

Sequence comparison

Multiple sequence alignment and partial order graphs

Motif discovery

Markov models of protein families

Classifiers and Kernels

Protein structure analysis

Protein Domains

II Putting all the pieces together: Clustering and classification

Embedding Algorithms and Vectorial Representations

Analysis of gene expression data

Protein-protein interactions

Cellular Pathways

Learning Gene Networks with Bayesian Networks.

Notes:

"A Chapman & Hall book."

Includes bibliographical references and index.

ISBN:

9781584885559

1584885556

OCLC:

672977443

Publisher Number:

2445448

99947240733