Radionanomedicine : combined nuclear and nanomedicine / Dong Soo Lee, editor.

Format:

Book

Author/Creator:

Lee, Dong Soo, 1957- author, editor.

Contributor:

Class of 1924 Book Fund.

Series:

Biological and medical physics, biomedical engineering 1618-7210

Biological and medical physics, biomedical engineering, 1618-7210

Language:

English

Subjects (All):

Nanomedicine.

Nuclear medicine.

Physical Description:

xxiv, 446 pages : illustrations (some color) ; 25 cm.

Place of Publication:

Cham, Switzerland : Springer, 2018.

Summary:

"This book describes radionanomedicine as an integrated medicine using exogenous and endogenous This book describes radionanomedicine as an integrated approach that uses exogenous and endogenous nanomaterials for in vivo and human applications. It comprehensively explains radionanomedicine comprising nuclear and nanomedicine, demonstrating that it is more than radionanodrugs and that radionanomedicine also takes advantage of nuclear medicine using trace technology, in which miniscule amounts of materials and tracer kinetic elucidate in vivo biodistribution. It also discusses exogenous nanomaterials such as inorganic silica, iron oxide, upconversion nanoparticles and quantum dots or organic liposomes labelled with radioisotopes, and radionanomaterials used for targeted delivery and imaging for theranostic purposes. Further, it examines endogenous nanomaterials i.e. extracellular vesicles labelled with radioisotopes, known as radiolabelled extracellular vesicles, as well as positron emission tomography (PET) and single photon emission computed tomography (SPECT), which elucidate the biodistribution and potential for therapeutic success"--Publisher.

Contents:

PART I. Exogenous Radionanomedicine. Exogenous Radionanomedicine: Inorganic Nanomaterials / Carolina A. Ferreira, Shreya Goel and Weibo Cai

Porphyrin and Phthalocyanine Radiolabeling / Venugopal Rajendiran, Sanjana Ghosh and Jonathan F. Lovell

Graphene-Based Nanomaterials / Je Min Yoo, Do Won Hwang and Byung Hee Hong

PART II. Endogenous Radionanomedicine. Endogenous Radionanomedicine: Extracellular Vesicles / Changjin Lee, Do Won Hwang and Yong Song Gho

Endogenous Radionanomedicine: Radiolabeling / Hongyoon Choi and Do Won Hwang

Endogenous Radionanomedicine: Biodistribution and Imaging / Hongyoon Choi and Dong Soo Lee

Endogenous Radionanomedicine: Validation of Therapeutic Potential / Seunggyun Ha and Dong Soo Lee

PART III. Surface Modification and Radiolabeling. Surface Modification of Radionanomedicine / Daiqin Chen and Hao Hong

Radiolabeling Method: Core/Surface Labeling, Chemical and Physical Labeling / Dong Soo Lee, Minseok Suh and Yun-Sang Lee

PART IV. Targeted Delivery with Click Chemistry. Click Chemistry for Radionanomedicine Platform / Yun-Sang Lee, Lingyi Sun and Dexing Zeng

Preservation of Ligand Functionality by Click Chemistry / James C. Knight and Bart Cornelissen

Bioorthogonal Reaction for Fluorine-18 Labeling / Dong Wook Kim

PART V. In Vivo Biodistribution Using PET and SPECT. Preclinical PET and SPECT for Radionanomedicine / Hyung-Jun Im and Gi Jeong Cheon

Tracer kinetics in Radionanomedicine / Jae Sung Lee, Seongho Seo and Dong Soo Lee

PART VI. Factors Affecting Biodistribution and Their Consequences. Size-, Shape-, and Charge-Dependent Pharmacokinetics of Radiolabeled Nanoparticles / Feng Chen

Polyethylene Glycolation (PEGylation) and the Similar / Dong Soo Lee and Yun-Sang Lee

Excretion and Clearance / Hyung-Jun Im

PART VII. Immune Response to Nanomaterials. Immune Response to PEGylated Nanomedicines: Impact of IgM Response / Amr S. Abu Lila and Tatsuhiro Ishida

Innate immunity to nanomaterials / Dong Soo Lee and Young Kee Shin

PART VIII. Prospects. Molecular Imaging Using Radionanomedicine / Yong-Il Kim and Dong Soo Lee

Therapeutic/Theranostic Use of Radionanomedicine / So Won Oh and Dong Soo Lee.

Notes:

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Class of 1924 Book Fund.

ISBN:

9783319677194

3319677195

OCLC:

1002128225