Extreme Hepatic Surgery and Other Strategies : Increasing Resectability in Colorectal Liver Metastases / edited by Eduardo de Santibañes, Victoria Ardiles, Fernando A. Alvarez, Virginia Cano Busnelli, Martin de Santibañes.

Format:

Book

Contributor:

Santibañes, Eduardo de, editor.

Ardiles, Victoria, editor.

Alvarez, Fernando A., editor.

Busnelli, Virginia Cano, editor.

Santibañes, Martin de, editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Medicine.

Hepatology.

Proctology.

Abdomen--Surgery.

Abdomen.

Cancer--Surgery.

Cancer.

Medicine & Public Health.

Surgical Oncology.

Abdominal Surgery.

Local Subjects:

Medicine & Public Health.

Surgical Oncology.

Abdominal Surgery.

Hepatology.

Proctology.

Physical Description:

1 online resource (XIX, 383 pages 170 illustrations, 137 illustrations in color.)

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2017.

System Details:

text file PDF

Summary:

This book describes the diagnoses; staging and management of patients with colorectal liver metastases initially considered unresectable and portrays the different strategies to increase resectability along with their tactics and tricks. Colorectal carcinoma is the third most commonly diagnosed cancer in the world and according to recent cancer statistics around 1.23 million patients are diagnosed each year. Of these patients, approximately 50% will develop liver metastases during the course of their disease and around 15-25% are found to have stage IV disease at diagnosis. Liver resection has been recognized as the treatment of choice for these patients, offering overall 5-year survival rates of up to 50-60% and the only hope for cure. However, at diagnosis only 10-20% of these patients are possibly amenable to surgical resection with curative intent. The possibility to achieve an R0 resection is many times limited by the amount and quality of the future liver remnant (FLR), being posthepatectomy liver failure (PHLF) the most feared and severe complication after major liver resections. With the years, diverse strategies have been developed with the intention to increase resectability by increasing the future liver remnant and/or reducing tumor size, e.g. ALPPS. Along with these techniques, associated surgeries are developed including multivisceral resections, which broadens even more the resectability for patients.

Contents:

Part I Introduction. 1. Introduction

2. Liver surgical anatomy

II. Global patient evaluation and oncological assessment

3. Resectability assessment with diagnostic imaging

4. Liver function evaluation before extreme liver surgery

5. Imaging-based preoperative planning

6. Choosing the best strategy. Multidisciplinary evaluation

III

Non-operative multimodal therapies

7. Conversion and neoadjuvant therapies

8. Portal embolization

9. Intraarterial chemotherapy

10. Radioembolization

IV. Surgical strategies

11. Anesthetics management

12. Intraoperative evaluation of resectability

13. Vascular control in major hepatic resections

14. Two-stage liver surgery

15. Two-stage liver surgery with portal occlusion

16 ALPPS

17. Parenchymal-sparing liver resections

18. Combined vascular resections

19. Ex-vivo liver surgery

20. Liver transplant

21. The roll of laparoscopy in advanced liver disease

V. Management of concomitant extrahepatic disease

22. Pulmonary metastases

23. Nodal involvement

24. Peritoneal disease

25. Adjacent organs invasion. Multivisceral resections

VI. Postoperative complications and their management

26. Complications of hepatic resections

VII. Palliative care

27. Palliative care in patients with extensive disease. .

Other Format:

Printed edition:

ISBN:

9783319138961

Access Restriction:

Restricted for use by site license.