Stroke Genetics / edited by Pankaj Sharma, James F. Meschia.

Format:

Book

Contributor:

Sharma, Pankaj (Neurologist), editor.

Meschia, James F., editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Medicine.

Human genetics.

Internal medicine.

Neurology.

Medicine & Public Health.

Internal Medicine.

Human Genetics.

Local Subjects:

Medicine & Public Health.

Neurology.

Internal Medicine.

Human Genetics.

Physical Description:

1 online resource (XII, 431 pages 39 illustrations, 26 illustrations in color.)

Edition:

Second edition 2017.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2017.

System Details:

text file PDF

Summary:

This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Contents:

Introduction

Familial stroke epidemiology

Association study results

GWAS

Aneurysms/carvernous/AVM

ICH/amyloid/microbleeds

CADASIL

Fabry

MELAS

Sickle

Other monogenic

White matter disease

Carotid atherosclerosis

Dissection

Pharmacogenomics

Non-Caucasian stroke genetics

Small vessel disease

Genetics of neuroimaging in stroke

Cerebrovenous thrombosis

Ethics.

Other Format:

Printed edition:

ISBN:

9783319562100

Access Restriction:

Restricted for use by site license.