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Immune Infertility : Impact of Immune Reactions on Human Fertility / edited by Walter K.H. Krause, Rajesh K. Naz.

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Springer Nature - Springer Medicine eBooks 2017 English International Available online

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Format:
Book
Contributor:
Krause, Walter (Walter K. H.), editor.
Naz, Rajesh K., editor.
SpringerLink (Online service)
Language:
English
Subjects (All):
Medicine.
Immunology.
Dermatology.
General practice (Medicine).
Gynecology.
Reproductive health.
Urology.
Medicine & Public Health.
Reproductive Medicine.
General Practice / Family Medicine.
Local Subjects:
Medicine & Public Health.
Reproductive Medicine.
Gynecology.
Urology.
Immunology.
General Practice / Family Medicine.
Dermatology.
Physical Description:
1 online resource (XI, 302 pages 33 illustrations, 19 illustrations in color.)
Edition:
Second edition 2017.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2017.
System Details:
text file PDF
Summary:
This book offers comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has four sections focusing on Sperm antigens, Antisperm antibodies (ASAs), Clinical impact of ASAs, and Immune contraception, and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.
Contents:
Part I Sperm antigens: Proteomics of spermatozoa
Sperm surface proteome
Methods of Analysis of Sperm Antigens Related to Fertility
Sperm functions influenced by immune reactions
Part II Antisperm antibodies (ASA): The immune privilege of the testis
Immune chemistry of ASA
Sperm-specific T cells
Site and risk factors of ASA production
Biologic substrates containing ASA
ASA in the female
Sperm immobilising ASA
Part III The clinical impact of sperm antibodies: Autoimmune infertility
Tests for sperm antibodies
Impact on fertility outcome
Sperm antibodies and assisted reproduction
Treatment of immune infertility
Part IV Immune contraception: Immunization with Sperm Antigens to Induce Contraception
Immune contraception in wildlife animals
Experience from Clinical Trials with Fertility Control Vaccines.
Other Format:
Printed edition:
ISBN:
9783319407883
Access Restriction:
Restricted for use by site license.

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