Development of In Vitro Maturation for Human Oocytes : Natural and Mild Approaches to Clinical Infertility Treatment / edited by Ri-Cheng Chian, Geeta Nargund, Jack Y. J. Huang.

Format:

Book

Contributor:

Chian, Ri-Cheng, editor.

Nargund, Geeta, editor.

Huang, Jack Y. J., editor.

SpringerLink (Online service)

Language:

English

Subjects (All):

Medicine.

Endocrinology.

Reproductive health.

Medicine & Public Health.

Reproductive Medicine.

Local Subjects:

Medicine & Public Health.

Reproductive Medicine.

Endocrinology.

Physical Description:

1 online resource (XVII, 376 pages 67 illustrations, 56 illustrations in color.)

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2017.

System Details:

text file PDF

Summary:

An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM. Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.

Contents:

Part I: Ovarian Function

Ovarian Endocrinology

Follicular Development and Oocyte Growth

A New Understanding of the Regulation of Oocyte Meiotic Prophase Arrest and Resumption

Mitochondria of the Oocyte

Part II: Natural Cycle IVF and Stimulation Cycle IVF

Natural Cycle IVF: Summary of the Current Literature

Follicular Fluid Hormone Profiles in Natural Cycle IVF Patients during Follicular Phase

Standard Ovarian Stimulation Protocols and Their Outcomes

Which Women Are Suitable for Natural and Modified Natural Cycle IVF?

Natural Cycle IVF with Spontaneous LH Surge

Etiologies and Risk Factors of Ovarian Hyperstimulation Syndrome

Prevention and Management of Ovarian Hyperstimulation Syndrome

Part III: Minimal or Mild Stimulation for IVF

Cumulative Pregnancy Rates after Six Cycles of Modified Natural Cycle IVF

Minimal Stimulation for IVF with Clomiphene Citrate

Mild Stimulation Protocols: Combination of Clomiphene Citrate and Recombinant FSH or HMG

Mild Stimulation Protocol for Poor Ovarian Responders Undergoing IVF

The Application of Natural Cycle IVF in Primary Ovarian Insufficiency

Mild Stimulation Protocols for Oncofertility Patients

Minimally Invasive IVF as an Alternative Treatment Option for Infertile Couples: (INVO) Procedure

Accessible Infertility Care: From Dream to Reality

Genetic Aspects of Recurrent Implantation Failure

Part IV: Development of In Vitro Maturation

IVM as Clinical Treatment: Overview

Avoidance of Severe Ovarian Hyperstimulation with IVM Treatment

Immature Oocyte Retrieval for IVM Treatment

Laboratory Aspect of IVM Treatment

Obstetric Outcomes of In Vitro Maturation Treatment and Risk of Congenital Malformations

Development of IVM Treatment: Combination of Natural Cycle IVF with IVM.

Other Format:

Printed edition:

ISBN:

9783319534541

Access Restriction:

Restricted for use by site license.