Antimicrobial photodynamic inactivation and antitumor photodynamic therapy with fullerenes / Lucas F. de Freitas, Michael R. Hamblin.

Format:

Book

Author/Creator:

Freitas, Lucas F. de (Lucas Freitas), author.

Contributor:

Morgan & Claypool Publishers, publisher.

Institute of Physics (Great Britain), publisher.

Series:

IOP (Series). Release 2.

IOP concise physics

[IOP release 2]

IOP concise physics, 2053-2571

Language:

English

Subjects (All):

Fullerenes--Therapeutic use.

Fullerenes.

Photochemotherapy.

Cancer--Photochemotherapy.

Cancer.

Fullerenes--therapeutic use.

Bacterial Infections--drug therapy.

Neoplasms--therapy.

Medical Subjects:

Fullerenes--therapeutic use.

Photochemotherapy.

Bacterial Infections--drug therapy.

Neoplasms--therapy.

Physical Description:

1 online resource (various pagings) : illustrations (some color).

Distribution:

Bristol [England] : IOP Publishing, [2016]

Place of Publication:

San Rafael [California] : Morgan & Claypool Publishers, [2016]

System Details:

Mode of access: World Wide Web.

System requirements: Adobe Acrobat Reader.

text file

Biography/History:

Dr. Lucas Freitas de Freitas received his PhD in bioengineering from the University of São Paulo, Brazil (2016). Part of his PhD research was done under the supervision of Dr. Hamblin. Dr. de Freitas has published in the biomedical field, especially on light interaction with microorganisms and with the human body. Dr. Michael Hamblin is a Principal Investigator at the Wellman Center for Photomedicine, Massachusetts General Hospital, an Associate Professor of Dermatology, Harvard Medical School and affiliated faculty at Harvard-MIT Division of Health and Science Technology.

Summary:

This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

Contents:

Preface

1. Introduction

2. Fullerenes

3. Resonant energy transfer

4. Photo-induced charge transfer

5. Fullerenes as photosensitizers

6. Chemical modifications

7. Examples of the synthesis of monocationic and polycationic fullerene derivatives

7.1. Synthesis of hexa-anionic fullerene derivatives

7.2. Synthesis of mono- or polycationic fullerene derivatives

7.3. Synthesis of chromophore-linked fullerene derivatives

7.4. The photophysics and photochemistry of fullerenyl molecular micelles and chromophore-fullerene conjugates

7.5. Synthesis of liposomal or micellar fullerenes

8. Photodynamic therapy

8.1. Traditional photosensitizers

9. Photosensitizer formulations for fullerene-mediated PDT

10. In vitro anti-cancer PDT with fullerenes

11. In vivo PDT for cancer

12. Antibiotic resistance and viral infections

13. General aspects of photodynamic inactivation of bacteria

14. In vitro antimicrobial PDT with fullerenes

15. In vivo antimicrobial PDT with fullerenes

16. Conclusions.

Notes:

"Version: 20160401"--Title page verso.

"A Morgan & Claypool publication as part of IOP Concise Physics"--Title page verso.

Includes bibliographical references.

Title from PDF title page (viewed on May 6, 2016).

Other Format:

Print version:

ISBN:

9781681742472

9781681741192

OCLC:

949173442

Access Restriction:

Restricted for use by site license.