Medicinal chemistry / Norma K. Dunlap, Donna M. Huryn.

Format:

Book

Author/Creator:

Dunlap, Norma, author.

Huryn, Donna M., author.

Language:

English

Subjects (All):

Pharmaceutical chemistry.

Chemotherapy.

Chemistry, Pharmaceutical.

Drug Therapy.

Medical Subjects:

Chemistry, Pharmaceutical.

Drug Therapy.

Physical Description:

xii, 495 pages ; 28 cm

Place of Publication:

New York , NY : Garland Science, Taylor & Francis Group, LLC, [2018]

Contents:

Historical perspective and overview of drug discovery

Drug discovery: hit and lead identification

Lead optimization: drug-target interactions and the pharmacophore

Lead optimization: properties optimized and medicinal chemistry strategies

The process of developing a drug from an optimized lead

Receptors, ion channels, and transporters as drug targets

Enzymes as drug targets

Protein-protein interactions and lipid structure interactions as drug targets

DNA and RNA as drug targets

Anti-cancer drugs

Antiviral and antifungal agents

Antibacterial and antiparasitic drugs

Drugs acting on the central nervous system.

Notes:

Includes bibliographical references and index.

ISBN:

9780815345565

0815345569

OCLC:

991671230

Publisher Number:

99976658589