Bugs as drugs : therapeutic microbes for the prevention and treatment of disease / edited by Robert A. Britton, Baylor College of Medicine, Molecular Virology and Microbiology, Houston, Texas, Patrice D. Cani, Université catholique de Louvain, Louvain Drug Research Institute, WELBIO-Walloon Excellence in Life Sciences, Brussels, Belgium.

Format:

Book

Contributor:

Britton, Robert A. (Robert Allen), editor.

Cani, Patrice D., editor.

ProQuest ebook central.

President Emeritus Martin Meyerson Fund.

Language:

English

Subjects (All):

Microorganisms--Therapeutic use.

Microorganisms.

Bacteria--Therapeutic use.

Bacteria.

Medical microbiology.

Probiotics.

Physical Description:

1 online resource (xiv, 499 pages)

Place of Publication:

Washington, DC : ASM Press, [2018]

System Details:

text file

Contents:

Cover; Half Title; Title Page; Copyright; Contents; Contributors; About the Editors; Preface; A. TRADITIONAL PROBIOTIC APPROACHES; Chapter 1: Biochemical Features of Beneficial Microbes: Foundations for Therapeutic Microbiology; BACKGROUND; SIGNALING COMPOUNDS; METABOLITES THAT BENEFIT THE HOST; ANTIMICROBIAL COMPOUNDS; SUMMARY AND CONCLUSIONS; CITATION; REFERENCES; Chapter 2: The Genomic Basis of Lactobacilli asÂ#x92;Health-Promoting Organisms; BENEFICIAL EFFECTS ASSOCIATED WITH LACTOBACILLI; GENOMIC DIVERSITY OF LACTOBACILLI; DISTRIBUTION OF PROBIOTIC-RELATED TRAITS IN LACTOBACILLI

INTRASPECIFIC DIVERSITY OF LACTOBACILLUS SPECIES HARBORING PROBIOTIC STRAINSTHE CONTROVERSY IN LACTOBACILLUS TAXONOMY; ACKNOWLEDGMENTS; CITATION; REFERENCES; Chapter 3: Bifidobacteria and Their Health-Promoting Effects; THE BIFIDOBACTERIUM GENUS; BIFIDOBACTERIA AS MEMBERS OF THE HUMAN INTESTINAL MICROBIOTA; BIFIDOBACTERIA AS PROBIOTICS; BIFIDOBACTERIA FOR PREVENTION AND TREATMENT OF DISEASE; CONCLUSIONS; ACKNOWLEDGMENTS; CITATION; REFERENCES; B. NEXT-GENERATION BACTERIOTHERAPY: OPPORTUNITIES IN CHRONIC DISEASES; Chapter 4: Microbial Interactions and Interventions in Colorectal Cancer

INTRODUCTIONTHE HOST SIDE: PHYSIOLOGY AND DEVELOPMENT IN COLORECTAL CANCER; COLONIC CRYPT; COLORECTAL CANCER; THE NORMAL COLONIC MICROBIOTA; WHEN THINGS GO AWRY: THE GUT MICROBIOTA ASSOCIATED WITH CRC; THE POTENTIAL FOR TREATING CRC WITH MICROBIAL MODULATION THERAPIES; CONCLUSION: CRC TREATMENT OF THE FUTUREâ#x80;#x94;WHERE DO WE GO FROM HERE?; CITATION; REFERENCES; Chapter 5: Microbial Impact on Host Metabolism: Opportunities for Novel Treatments of Nutritional Disorders?; INTRODUCTION; MICROBIAL CONTRIBUTIONS TO ENERGY HOMEOSTASISâ#x80;#x94;INSIGHTS FROM GERMFREE MICE

IMPACT OF THE GUT MICROBIOTA ON MALNUTRITION-ASSOCIATED METABOLIC DISORDERSGUT MICROBES IN CHILDHOOD UNDERNUTRITION; CONCLUSION AND PERSPECTIVES; ACKNOWLEDGMENTS; CITATION; REFERENCES; Chapter 6: Therapeutic Opportunities in the Vaginal Microbiome; SCOPE OF THIS REVIEW; THE CERVICOVAGINAL MICROBIOME AND ITS INFLUENCE ON HEALTH; TARGETS FOR THERAPY: MECHANISMS WHEREBY LACTOBACILLI PROTECT THE HOST; COMMUNITY PROBIOTICS; SUMMARY; ACKNOWLEDGMENTS; CITATION; REFERENCES; Chapter 7: Lung Microbiota and Its Impact on theÂ#x92;Mucosal Immune Phenotype; INTRODUCTION

UNIQUE CHALLENGES IN EVALUATING THE LUNG MICROBIOMESOURCES OF MICROBIAL CHALLENGE TO THE LOWER AIRWAYS; UNIQUE SELECTION PRESSURES OF THE LOWER AIRWAY MICROBIOME; THE LUNG MICROBIOME IN DISEASE STATES; THE LUNG-GUT AXIS AND ITS ROLE IN DISEASE; MICROBIOTA EFFECTS ON THE ACTIVATION OF INFLAMMATORY PATHWAYS OF THE LOWER AIRWAY ENVIRONMENT; CONCLUSION; ACKNOWLEDGMENTS; CITATION; REFERENCES; Chapter 8: Microbiota, Liver Diseases, and Alcohol; METABOLIC LIVER DISEASES: FROM DIAGNOSIS TO CURRENT TREATMENTS; NAFLD AND THE GUT MICROBIOTA; ALCOHOL LIVER DISEASE; ADVANCED LIVER DISEASE; CONCLUSION

Notes:

Includes bibliographical references and index.

Electronic reproduction. Ann Arbor, MI Available via World Wide Web.

Description based on online resource; title from digital title page (viewed on January 30, 2018).

Local Notes:

Acquired for the Penn Libraries with assistance from the President Emeritus Martin Meyerson Fund.

Other Format:

Print version: Bugs as drugs

ISBN:

9781555819705

1555819702

Publisher Number:

99976356447

Access Restriction:

Restricted for use by site license.